主观记忆抱怨的MRI研究进展  

Research progress on MRI of subjective memory complaints

作　　者：王佳佳 任庆国[1,2] 袁子怡 孟祥水(审校) WANG Jiajia;REN Qingguo;YUAN Ziyi;MENG Xiangshui(Department of Radiology,Qilu Hospital of Shandong University,Qingdao 266011,China;Qingdao Key Laboratory of Medical Imaging and Medical-industrial Intersection)

机构地区：[1]山东大学齐鲁医院放射科,青岛266011 [2]青岛市医学影像医工交叉重点实验室

出　　处：《国际医学放射学杂志》2024年第4期458-462,共5页International Journal of Medical Radiology

基　　金：山东省自然科学基金面上项目(ZR2023MH042);青岛市自然科学基金项目(23-2-1-201-zyyd-jch)。

摘　　要：主观记忆抱怨(SMC)是阿尔茨海默病(AD)疾病谱病人的极早期表现,且会出现特定脑结构的变化。近年来,多种MRI技术已用于SMC的研究,包括结构MRI(sMRI)和扩散MRI(dMRI)技术,可以通过测量灰质体积、白质高信号(WMH)负荷,以及多种扩散张量成像(DTI)参数、峰度参数和自由水体积分数(FWVF)等指标来评价SMC。就sMRI及dMRI在SMC中的研究进展进行综述,以期为SMC的早期识别和干预提供依据。Subjective memory complaints(SMC)are an extremely early manifestation of the Alzheimer’s disease(AD)spectrum,associated with changes in specific brain structures.In recent years,a variety of MRI techniques have been used in the study of SMC,including structural MRI(sMRI)and diffusion MRI(dMRI).These techniques can be used to evaluate SMC by measuring grey matter volume,white matter hyperintensity(WMH)load,as well as a wide range of diffusion tensor imaging(DTI)parameters,kurtosis parameters,and free water volume fraction(FWVF).The research progress of sMRI and dMRI in SMC is reviewed to provide a basis for the early identification and intervention of SMC.

关 键 词：主观记忆抱怨 白质高信号 磁共振成像 扩散张量成像 扩散峰度成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R749.1[医药卫生—诊断学]