Clinical features and risk factors for invasive fungal sinusitis after allogeneic hematopoietic stem cell transplantation  

作　　者：付海霞 FU Haixia(Peking Univ People's Hosp,Peking Univ Insit Hematol,Natl Clin Hematol Dis Res Center,Beijing Hematopoiet Stem Cell Transplant Key Lab,Beijing 100044)

机构地区：[1]Peking Univ People's Hosp,Peking Univ Insit Hematol,Natl Clin Hematol Dis Res Center,Beijing Hematopoiet Stem Cell Transplant Key Lab,Beijing 100044

出　　处：《China Medical Abstracts(Internal Medicine)》2024年第2期118-119,共2页中国医学文摘（内科学分册（英文版）

摘　　要：Objective To analyze the clinical characteristics and outcomes of patientswith invasive fungal sinusitis(invasive fungal rhinosinusitis,IFR)after allogeneic hematopoietic stem cell transplantation(allo-HSCT)and explored the risk factors for IFR after allo-HSCT.Methods Nineteen patients with IFR after allo-HSCT at Peking University People's Hospital from January 2012 to December 2021 were selected as the study group,and 95 patients without IFR after allo-HSCT during this period were randomly selected as the control group(1:5 ratio).Results Nineteen patients,including 10 males and 9 females,had IFR after allo-HSCT.The median age was 36(10-59)years.The median IFR onset time was 68(9-880)days after allo-HSCT.There wereseven patients with acute myeloid leukemia,five with acute lymphoblastic leukemia,two with myelodysplastic syndrome,two with chronic myeloid leukemia,one with acute mixed-cell leukemia,one with multiple myeloma,and one with T-lymphoblastic lymph node tumor.There were 13 confirmed cases and 6 clinically diagnosed cases.The responsible fungus was Mucor in two cases,Rhizopus in four,Aspergillus in four,and Candida in three.

关 键 词：IFR RATIO INVASIVE 

分 类 号：R457.7[医药卫生—治疗学] R765[医药卫生—临床医学]