孕妇不同孕期D-二聚体、凝血四项检测的临床意义  

The clinical significance of D-dimer and coagulation tests in pregnant women at different stages of pregnancy

作　　者：陈艳[1] 祁从辉 李进[2] Chen Yan;Qi Conghui;Li Jin(Department of Obstetrics and Gynecology,The Third People's Hospital of Jianhu County,Yancheng 224700,China;Department of Laboratory,The Third People's Hospital of Jianhu County,Yancheng 224700,China)

机构地区：[1]江苏省建湖县第三人民医院妇产科,江苏盐城224700 [2]江苏省建湖县第三人民医院检验科,江苏盐城224700

出　　处：《实用妇科内分泌电子杂志》2024年第17期104-106,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨凝血四项和D-二聚体检测在孕妇中的临床应用价值。方法收集本院就诊建卡的90例正常妊娠孕妇的临床资料,其中孕早期、孕中期及孕晚期各30例。检测并比较不同时期孕妇的活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)、纤维蛋白原(FIB)、凝血酶时间(TT)和D-二聚体。结果孕妇的PT、APTT、TT随着孕周增加而缩短,FIB和D-二聚体水平随着孕周增加而增加,差异具有统计学意义(P<0.05)。结论对孕妇进行凝血四项和D-二聚体的联合动态监测,能够及时掌握孕妇体内的凝血状态,有效预防分娩或产后大出血及血栓性疾病的发生,全面保证孕妇及胎儿的生命安全。Objective To explore the clinical application value of four coagulation tests and D-dimer detection in pregnant women.Methods Clinical data were collected from 90 normal pregnant women who received medical treatment in our hospital,including 30 cases in early pregnancy,30 cases in mid pregnancy,and 30 cases in late pregnancy.Detect and compare the activated partial thromboplastin time(APTT),prothrombin time(PT),fibrinogen(FIB),thrombin time(TT),and D-dimer levels of pregnant women at different stages.Results The PT,APTT,and TT of pregnant women shortened with increasing gestational age,while the levels of FIB and D-dimer increased with increasing gestational age,and the differences were statistically significant(P<0.o5).Conclusion The combined dynamic monitoring of the four coagulation parameters and D-dimer in pregnant women can timely grasp the coagulation status in the body of pregnant women,effectively prevent the occurrence of postpartum hemorrhage and thrombotic diseases,and comprehensively ensure the life safety of pregnant women and fetuses.

关 键 词：孕妇 凝血四项 D-二聚体 凝血状态 

分 类 号：R446.1[医药卫生—诊断学] R714[医药卫生—临床医学]