低剂量呼气相胸部CT参数与慢性支气管炎肺功能的关系分析  

Analysis of the Relationship between Low-dose Expiratory Chest CT Parameters and Lung Function in Chronic Bronchitis

作　　者：郭子祺 田茜 廉丽敏[1] GUO Zi-qi;TIAN Qian;LIAN Li-min(CT Room,The First People's Hospital of Xinxiang,Xinxiang 453000,Henan Province,China)

机构地区：[1]河南省新乡市第一人民医院CT室,河南新乡453000

出　　处：《罕少疾病杂志》2024年第7期43-45,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的分析低剂量呼气相胸部CT参数与慢性支气管炎肺功能的关系。方法选取2022年1月~2022年12月本院诊治的112例慢性支气管炎患者作为疾病组,另选取同期在本院体检中心体检的112例健康志愿者作为对照组。两组均行低剂量呼气相胸部CT扫描和肺功能检查,记录CT参数[肺容积、肺野密度、空气潴留区域肺组织容积占全肺容积的百分比(LAA%)]和肺功能指标[第1秒用力呼气容积(FEV1)、用力肺活量(FVC)、FEV1与FVC的比值(FEV1/FVC)、FEV1占预测值百分比(FEV1%)、FVC占预测值百分比(FVC%)、血氧分压(PaO2)、二氧化碳分压(PaCO2)]。采用Pearson法分析低剂量呼气相胸部CT参数与慢性支气管炎肺功能指标的相关性。结果疾病组肺容积、肺野密度、LAA%和PaCO2均高于对照组(P<0.05),FEV1/FVC、FEV1%、FVC%、PaO2均低于对照组(P<0.05);急性发作期肺容积、肺野密度、LAA%、PaCO2均高于慢性迁延期和临床缓解期(P<0.05),慢性迁延期均高于临床缓解期(P<0.05);急性发作期FEV1/FVC、FEV1%、FVC%、PaO2均低于慢性迁延期和临床缓解期(P<0.05),慢性迁延期均低于临床缓解期(P<0.05);Pearson分析结果显示,肺容积、肺野密度、LAA%与FEV1/FVC、FEV1%、FVC%、PaO2均呈负相关(P<0.05),与PaCO2均呈正相关(P<0.05)。结论慢性支气管炎患者低剂量呼气相胸部CT参数与肺功能指标存在相关性,可为临床科学治疗慢性支气管炎提供影像学参考依据。Objective To analyze the relationship between low-dose expiratory chest CT parameters and lung function in chronic bronchitis.Methods 112 patients with chronic bronchitis diagnosed and treated in our hospital from January 2022 to December 2022 were selected as the disease group,and 112 healthy volunteers who were examined in the physical examination center of our hospital during the same period were selected as the control group.Both groups underwent low-dose expiratory chest CT scans and lung function examinations,CT parameters[lung volume,lung field density,percentage of lung tissue volume in air trapping area to total lung volume(LAA%)]and lung function indicators[forced expiratory volume in the first second(FEV1),forced vital capacity(FVC),ratio of FEV1 to FVC(FEV1/FVC),percentage of FEV1 to predicted value(FEV1%),percentage of FVC to predicted value(FVC%),partial pressure of blood oxygen(PaO2),partial pressure of carbon dioxide(PaCO2)]were recorded.The Pearson method was used to analyze the correlation between low-dose expiratory chest CT parameters and lung function indicators in chronic bronchitis.Results The lung volume,lung field density,LAA%and PaCO2 in the disease group were higher than those in the control group(P<0.05),while FEV1/FVC,FEV1%,FVC%and PaO2 were lower than those in the control group(P<0.05).Lung volume,lung field density,LAA%and PaCO2 in acute exacerbation were all higher than those in chronic exacerbation and clinical remission(P<0.05),while those in chronic exacerbation were higher than those in clinical remission(P<0.05).The FEV1/FVC,FEV1%,FVC%and PaO2 in acute exacerbation were lower than those in chronic exacerbation and clinical remission(P<0.05),while those in chronic exacerbation were lower than those in clinical remission(P<0.05).Pearson analysis results showed that lung volume,lung field density and LAA%were negatively correlated with FEV1/FVC,FEV1%,FVC%,and PaO2(P<0.05),and positively correlated with PaCO2(P<0.05).Conclusion There is a correlation between low-dose expiratory ch

关 键 词：低剂量 呼气相 胸部CT参数 慢性支气管炎 肺功能 相关性 

分 类 号：R562.21[医药卫生—呼吸系统]