TyG-BMI联合血尿酸对2型糖尿病合并非酒精性脂肪性肝病的预测价值  

Predictive Value of TyG-BMI Combined with Blood Uric Acid in Type 2 Diabetes Mellitus with Non-alcoholic Fatty Liver Disease

作　　者：白伟 李帅 BAI Wei;LI Shuai(Clinical Laboratory,Shangqiu Municipal Hospital,Shangqiu 476000,Henan Province,China;Clinical Laboratory,Henan Hongli Hospital,Changyuan 453400,Henan Province,China)

机构地区：[1]商丘市立医院检验科,河南商丘476000 [2]河南宏力医院检验科,河南长垣453400

出　　处：《罕少疾病杂志》2024年第7期68-70,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的探讨甘油三脂葡萄糖体重指数(TyG-BMI)联合血尿酸(SUA)对2型糖尿病(T2DM)合并非酒精性脂肪性肝(NAFLD)的预测价值。方法回顾T2DM合并NAFLD 84例患者资料作合并组,选取同期未合并NAFLD 52例患者作未合并组。多因素Logistic回归模型分析危险因素。受试者工作特征曲线(ROC)分析预测价值。结果合并组体质量指数(BMI)、腰臀比(WHR)、总胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)及胰岛素抵抗指数(HOMA-IR)、糖化血红蛋白(HbAlc)、谷丙转氨酶(ALT)、谷草转氨酶(AST)、SUA、甘油三脂葡萄糖(TyG)、TyG-BMI水平高于未合并组,HDL-C水平低于未合并组(P<0.05)。Logistic回归分析显示,高水平的WHR、HOMA-IR、SUA、TyG、TyG-BMI均是导致NAFLD发生的危险因素(P<0.05)。ROC曲线显示,TyG-BMI联合SUA的AUC为0.905,高于任一单项指标(P<0.05)。结论TyG-BMI联合SUA对预测T2DM发生NAFLD具有较高效能。Objective To explore the predictive value of triglyceride lipid glucose body mass index(Ty G-BMI)combined with blood uric acid(SUA)for type 2 diabetes mellitus(T2DM)combined with non-alcoholic fatty liver(NAFLD).Methods:The data of T2DM with NAFLD 84 patients were reviewed as the combined group,and the patients without NAFLD 52 cases were selected as the uncombined group.Multivariate Logistic regression model was used to analyze risk factors.Predictive value of receiver operating characteristic curve(ROC)analysis.Results:Combined group mass index(BMI),waist-hip ratio(WHR),total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C)and insulin resistance index(HOMA-IR),glycylated hemoglobin(HbAlc),glutamaminase(ALT),glutamaminase(AST),SUA,triglycericose glucose(Ty G),and the lower HDL-C than the uncombined group(P<0.05).Logistic Regression analysis showed that high levels of WHR,HOMA-IR,SUA,TyG,and TyG-BMI were all risk factors for the development of NAFLD(P<0.05).The ROC curve showed that the AUC of Ty G-BMI combined with SUA was 0.905,higher than any individual indicator(P<0.05).Conclusion:Ty G-BMI and SUA can effectively predict NAFLD in T2DM.

关 键 词：2型糖尿病 非酒精性脂肪性肝 甘油三脂葡萄糖体重指数 血尿酸 预测 

分 类 号：R589.2[医药卫生—内分泌]