血常规联合心肌标志物检测对冠心病的诊断价值分析  

Diagnostic value of blood routine test combined with myocardial markers in patients with coronary heart disease

作　　者：张晓飞 纪凌云 黄兆杰 李志军 杨冀[1] ZHANG Xiaofei;JI Lingyun;HUANG Zhaojie;LI Zhijun;YANG Ji(Department of Laboratory Medicine,Shanghai EastHospital,Tongji University School of Medicine,Shanghai 200123,China)

机构地区：[1]同济大学附属东方医院检验科,上海200123

出　　处：《国际检验医学杂志》2024年第S01期140-143,共4页International Journal of Laboratory Medicine

摘　　要：目的探讨血常规与心肌标志物检测在冠心病中的诊断效果及价值。方法选取2022年5月至2023年5月该院收治的100例冠心病患者纳入观察组,并选取同期100例健康体检者纳入对照组,对两组入选对象血常规指标与心肌标志物指标进行检测,观察对比入选对象的血常规相关指标水平以及心肌标志物相关指标水平。结果观察组红细胞体积分布宽度(RDW)指标水平均明显高于对照组,差异有统计学意义(P<0.05);观察组PDW、血小板总数(PLT)、平均血小板体积(MPV)以及血小板比容(PCT)等指标水平相较于对照组,差异无统计学意义(P>0.05);观察组超敏心肌肌钙蛋白(hs-cTnT)、心肌肌钙蛋白I(cTnl)、心肌肌钙蛋白(cTnT)以及肌醇激酶同工酶(CK-MB)等指标水平均较对照组高,差异有统计学意义(P<0.05);重度狭窄组患者RDW、cTnl、cTnT以及CK-MB等指标水平均显著高于中度狭窄组,差异有统计学意义(P<0.05)。结论冠心病患者血常规中的RDW指标水平具有明显的升高现象,且心肌标志物指标在冠心病患者中均会发生异常变化,因此血常规检测联合心肌标志物检测在诊断冠心病中具有较高的应用价值。Objective To explore the diagnostic effect and value of combined detection of blood routine ex-amination and myocardial markers in patients with coronary heart disease.Methods From May 2022 to May 2023,100 patients with coronary heart disease were selected as the observation group,and 100 healthy subjects were selected as the control group,to observe and compare the levels of blood routine and myocardial markers in the selected subjects.Results The RDW index level in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05),and there were no signifi-cant differences in PDW,Plt,MPV and PCT levels between the observation group and the Control Group(P>0.05),the levels of hs-cTnT,CTNL,CTNT and CK-MB in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The levels of RDW,CTNL,CTNT and CK-MB in severe stenosis group were significantly higher than those in moderate stenosis group,and the differences were statistically significant(P<0.05).Conclusion The RDW index level in the blood routine of patients with coronary heart disease is obviously increased,and the index of myocardial markers will have abnormal changes in the patients with coronary heart disease,therefore,routine blood test combined with myocardial markers detection in the diagnosis of coronary heart disease has a higher application value.

关 键 词：冠心病 血常规 心肌标志物 检测 诊断价值 

分 类 号：R541.4[医药卫生—心血管疾病] R446.11[医药卫生—内科学]