专性捕食细菌——蛭弧菌及其类似细菌的捕食机制及其应用前景  

Predation mechanism and potential application of specific predatory bacteria:Bdellovibrio and like organisms

作　　者：谭述新 黄巧云 陈雯莉[1,2] TAN Shuxin;HUANG Qiaoyun;CHEN Wenli(National Key Laboratory of Agricultural Microbiology,Wuhan 430070,China;College of Life Science and Technology,Huazhong Agricultural University,Wuhan 430070,China;Hubei Province Key Laboratory of Soil Environment and Pollution Remediation/College of Resources and Environment,Huazhong Agricultural University/National Key Laboratory of Soil Health Diagnosis and Green Restoration for Environmental Protection,Wuhan 430070,China)

机构地区：[1]农业微生物资源发掘与利用全国重点实验室,武汉430070 [2]华中农业大学生命科学技术学院,武汉430070 [3]土壤环境与污染修复湖北省重点实验室/华中农业大学资源与环境学院/国家环境保护土壤健康诊断与绿色修复重点实验室,武汉430070

出　　处：《华中农业大学学报》2024年第4期60-69,共10页Journal of Huazhong Agricultural University

基　　金：国家自然科学基金项目(42020104003);国家重点研发计划项目(2020YFC1806803)。

摘　　要：专性捕食细菌蛭弧菌及其类似细菌(Bdellovibrio and like organisms,BALOs)因在农业、工业和医学,尤其是在治疗抗生素耐药病原细菌感染中的潜在应用前景而倍受重视。但关于BALOs的诸多基础科学问题在过去几十年里一直不清楚,这也是这类细菌暂未被有效开发和利用的根本原因。近年来,关于BALOs生命周期、捕食机制、资源分布与多样性以及它们在医学、农业和工业中的应用等方面取得了较多进展,特别是2021年蛭弧菌门正式确立以来,相关研究暴发式增长。本文系统回顾BALOs的研究进展,并着重介绍最新报道的捕食机制研究等突出成就,以促进我们对BALOs资源的认识与进一步应用,并指导未来的BALOs研究。The specific predatory bacteria Bdellovibrio and like organisms(BALOs)are been highly valued due to their potential applications in agriculture,industry and medicine,especially in treating the infections caused by pathogenic bacteria with antibiotic resistance.However,many fundamental scientific issues regarding BALOs have been unclear in the past decades,which is the bottom cause why these types of bacteria have not been effectively developed and utilized yet.In recent years,significant progress has been made in the life cycle,mechanisms of predation,the distribution of resource and the diversity of BALOs,and the applications of BALOs in medicine,agriculture,and industry.Especially since the formal establishment of the phylum Bdellovibrionota in 2021,there has been an explosive growth in studies related to BALOs.This article systematically reviewed the progress on studying BALOs.It was focused on introducing the latest reports on predatory mechanisms of BALOs and other outstanding achievements to promote the understanding and further application of BALOs resources,and to guide the studies on BALOs in the future.

关 键 词：捕食者 噬菌蛭弧菌 蛭弧菌及其类似细菌 微生物资源 抗生素耐药 

分 类 号：N1[自然科学总论] N55