经导管主动脉瓣置换术后瓣周漏相关危险因素研究进展  

Risk Factors Related to Perivalvular Leakage After Transcatheter Aortic Valve Replacement

作　　者：吴奕璇 邓少东 陈建英 WU Yixuan;DENG Shaodong;CHEN Jianying(Guangdong Medical University,Zhanjiang 524000,Guangdong,China;Affiliated Hospital of Guangdong Medical University,Zhanjiang 524000,Guangdong,China)

机构地区：[1]广东医科大学,广东湛江524000 [2]广东医科大学附属医院,广东湛江524000

出　　处：《心血管病学进展》2024年第6期481-483,488,共4页Advances in Cardiovascular Diseases

基　　金：国家自然科学基金(81370242);广东省2023年度省级大学生创新创业训练计划项目(S202310571076);湛江市科技计划项目(2022A01166,2022A01183);湛江市非资助科技攻关计划项目(2021B01145);广东医科大学青年科研培育基金(GDMUQ2021011);广东医科大学校级大学生创新创业训练计划项目(GDMU2021163,GDMU2021207)。

摘　　要：经导管主动脉瓣置换术(TAVR)目前已成为主动脉瓣狭窄患者的主要治疗方式之一,瓣周漏(PVL)是TAVR术后的常见并发症之一,轻度PVL可以影响患者的远期生存率,中、重度PVL是TAVR术后死亡率的独立预测因素。明确PVL的相关危险因素,可以较大程度上避免严重PVL的发生,改善TAVR术后患者的远期预后,现主要介绍PVL相关危险因素的研究进展。Transcatheter aortic valve replacement(TAVR)has become one of the main treatment options for patients with aortic stenosis.Perivalvular leakage(PVL)is a common complication after TAVR,and mild PVL can affect the long-term survival of patients,while moderate to severe PVL is an independent predictor of mortality after TAVR.Identifying the relevant risk factors for PVL can greatly reduce the occurrence of severe PVL and improve the long-term prognosis of patients after TAVR.This article mainly introduces the research progress on the risk factors related to PVL.

关 键 词：经导管主动脉瓣置换术 瓣周漏 主动脉瓣狭窄 

分 类 号：R654.2[医药卫生—外科学]