亚临床心血管疾病和多囊卵巢综合征相关性的研究进展  

Research progress of the association between subclinical cardiovascular disease and polycystic ovary syndrome

作　　者：胡燕丽(综述) 吕富荣(审校)[1] HU Yanli;LYU Furong(Department of Radiology,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China)

机构地区：[1]重庆医科大学附属第一医院放射科,重庆400010

出　　处：《现代医药卫生》2024年第14期2476-2480,共5页Journal of Modern Medicine & Health

基　　金：重庆市科技局自然科学基金项目(cstc2018jscx-mszdX0042)。

摘　　要：多囊卵巢综合征(PCOS)影响着全球6%~10%的女性,其典型特征是雄激素过多症、月经不调、不孕和超声显示多囊卵巢。此外,PCOS与多种内分泌和代谢紊乱有关,包括肥胖、胰岛素抵抗和糖尿病、高血压、血脂异常和代谢综合征,这些都会增加亚临床心血管疾病(CVD)的风险,但仅仅是血管内皮功能改变而无明显的CVD症状。该文通过检索最新文献,总结了PCOS患者和亚临床CVD关系的相关证据,包括血管舒张功能(FMD)、动脉僵硬、冠状动脉钙化(CAC)评分、颈动脉内中膜厚度(CIMT)及内脏和心外膜脂肪等标志物,以更好地说明PCOS患者与亚临床CVD的关系及最新的研究进展。Polycystic ovary syndrome(PCOS)affects about 6%-10%of women all over the world and is characterized by hyperandrogenism,menstrual irregularities,infertility,and ultrasonographic polycystic ovaries.In addition,PCOS is related to most of endocrine and metabolic disorders,including insulin resistance,obesity and diabetes,hypertension,dyslipidemia,and metabolic syndrome,all of which increase the risk of subclinical cardiovascular disease(CVD),but only with changes in vascular endothelial function without significant CVD symptoms.By searching the latest literature,this paper summarized the relevant evidence of the relationship between PCOS patients and subclinical CVD,including flow-mediated dilation(FMD),arterial stiffness,coronary artery calcium(CAC)score,visceral and epicardial fat and carotid intima-media thickness(CIMT)and so on,to better illustrate the relationship and the latest research progress between the PCOS patients with subclinical CVD.

关 键 词：多囊卵巢综合征 亚临床心血管疾病 预测 标志物 综述 

分 类 号：R711[医药卫生—妇产科学]