强化血糖控制治疗肺结核合并糖尿病患者的效果及可行性分析  

Effect and Feasibility Analysis of Intensive Blood Glucose Control in The Treatment of Pulmonary Tuberculosis Patients with Diabetes

作　　者：王海丽 WANG Haili(Department of Infectious Diseases,Suqian Infectious Disease Hospital,Suqian 223800,Jiangsu,China)

机构地区：[1]宿迁市传染病医院感染科,江苏宿迁223800

出　　处：《糖尿病新世界》2024年第9期77-79,83,共4页Diabetes New World Magazine

摘　　要：目的探究强化血糖控制对肺结核合并糖尿病患者的治疗效果。方法选取2022年12月—2023年12月宿迁市传染病医院收治的68例肺结核合并糖尿病患者为研究对象,按照奇偶数法分为对照组(34例)、研究组(34例)。对照组采取常规治疗,研究组采取强化血糖控制治疗。比较两组治疗总有效率、不良反应发生率、血糖指标及胰岛功能、血糖变异性指标。结果研究组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。治疗后,研究组空腹血糖、餐后2 h血糖、糖化血红蛋白水平低于对照组,胰岛素分泌指数高于对照组,差异有统计学意义(P均<0.05)。研究组空腹血糖变异系数低于对照组,全天血糖标准差低于对照组,血糖最大波动幅度小于对照组,差异有统计学意义(P均<0.05)。结论强化血糖控制方案对肺结核合并糖尿病的临床治疗效果显著,不良反应少,具有临床应用价值。Objective To explore the therapeutic effect of intensive blood glucose control on patients with pulmonary tuberculosis complicated with diabetes.Methods A total of 68 patients with tuberculosis combined with diabetes admitted to Suqian Infectious Disease Hospital from December 2022 to December 2023 were selected as the study objects,and they were divided into control group(34 cases)and research group(34 cases)according to odd-even method.The control group received conventional treatment,and the study group received intensive blood glucose control.The total effective rate,the incidence of adverse reactions,blood glucose index,islet function and blood glucose variability index were compared between the two groups.Results The total effective rate of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).After treatment,fasting blood glucose,2-hour postprandial blood glucose,glycated hemoglobin levels in the study group were lower than those in the control group,and insulin secretion index was higher than those in the control group,and the differences were statistically significant(all P<0.05).The fasting blood glucose variation coefficient,the standard deviation of blood glucose throughout the day and the maximum fluctuation range of blood glucose in the study group were lower than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion Intensive blood glucose control program has significant clinical effect on pulmonary tuberculosis complicated with diabetes and less adverse reactions,and has clinical application value.

关 键 词：肺结核 糖尿病 强化血糖控制 血糖水平 胰岛功能 

分 类 号：R587.1[医药卫生—内分泌]