蛋白质组科学数据库建设及应用  

Current status and applications of proteomic databases

作　　者：刘祎 徐小放 马洁 陈涛 朱云平 LIU Yi;XU XiaoFang;MA Jie;CHEN Tao;ZHU YunPing(State Key Laboratory of Proteomics,Beijing Proteome Research Center,National Center for Protein Sciences(Beijing),Beijing Institute of Lifeomics,Beijing 102206,China)

机构地区：[1]军事科学院军事医学研究院生命组学研究所,国家蛋白质科学中心(北京),北京蛋白质组研究中心,蛋白质组学国家重点实验室,北京102206

出　　处：《中国科学：生命科学》2024年第6期1101-1108,共8页Scientia Sinica(Vitae)

摘　　要：蛋白质组技术的发展及推广应用使蛋白质组数据共享的需要日益迫切,在数据共享理念的支撑下,蛋白质组数据库不断涌现.本文首先介绍了蛋白质组科学数据库的建设情况,重点阐述了国际蛋白质组数据联盟以及成员的现状,详细介绍了中国的蛋白质组数据库iProX,然后简要介绍了当前蛋白质组学数据库应用的四个方向,最后对该领域存在的挑战和机遇进行了展望.The development and application of proteomic technology make the need for proteome data sharing increasingly urgent.Supported by the concept of data sharing,proteomic databases continue to emerge.The databases effectively maintain the consistency and integrity of the data information,reduce data redundancy,and facilitate effective retrieval and access by users.This paper first introduces the status of proteomic databases,focuses on the International Proteomic Data Consortium and its members,introduces the Chinese proteomic database iProX in detail,then briefly introduces the application of proteomic database,and finally looks forward to the challenges and opportunities in this field.

关 键 词：蛋白质组学 数据库 数据共享 

分 类 号：Q811.4[生物学—生物工程]