An Overview of Chemical Constituents, Medicinal Properties, Clinical Trials, and Patents of Twigs of Morus alba(Ramulus Mori)  

作　　者：Eric Wei Chiang Chan Hung Tuck Chan Siu Kuin Wong 

机构地区：[1]Department of Food Science and Nutrition,Faculty of Applied Sciences,UCSI University,Cheras,Kuala Lumpur,Malaysia [2]Secretariat of International Society for Mangrove Ecosystems,Faculty of Agriculture,University of the Ryukyus,Okinawa,Japan [3]School of Foundation Studies,Xiamen University Malaysia,Sepang,Selangor,Malaysia

出　　处：《World Journal of Traditional Chinese Medicine》2024年第2期149-158,共10页世界中医药杂志（英文）

基　　金：the financial support provided by the Ministry of Higher Education (MOHE) Malaysia under the Fundamental Research Grant Scheme (FRGS) with grant code (FRGS/1/2022/STG04/UCSI/02/2)。

摘　　要：The rich chemical constituents and diverse pharmacological properties of Ramulus Mori(RM) or the twig of Morus alba with evidence supported by clinical trials and patents are reviewed. Known as Sangzhi in Chinese, RM is widely used in traditional Chinese medicine to treat gout, arthritis, and rheumatism. Chemical constituents include flavonoids, benzofurans, alkaloids, stilbenes, chalcones, phenolic acids, and coumarins. Bioactivities of RM include antidiabetic, anti-obesity, anti-inflammatory, antityrosinase, neuroprotective, antioxidant, hepatoprotective, cytoprotective, renoprotective, antihyperuricemic, analgesic, antifungal, DNA protective, anticancer, gastroprotective, cardioprotective, anti-hair aging, anti-arthritic, and antiplatelet aggregation properties. The most active compounds from RM are mulberrin, oxyresveratrol, and mulberroside A. All four clinical trials on RM are focused on the treatment of diabetes. The patents entail using RM extracts as cosmetics for skin whitening and as agents for hypoglycemia. Topics for further research on RM are suggested.

关 键 词：Clinical trials mulberrin mulberroside A OXYRESVERATROL patents Sangzhi 

分 类 号：R282.71[医药卫生—中药学]