《慢性阻塞性肺疾病全球创议(2024版)》解读:一秒率正常的肺功能受损  

Interpretation of the Global Initiative for Chronic Obstructive Lung Disease(2024 report):preserved ratio impaired spirometry

作　　者：褚岚和 陈亚红[1] Chu Lanhe;Chen Yahong(Department of Respiratory and Critical Care Medicine,Peking University Third Hospital,Beijing 100191,China)

机构地区：[1]北京大学第三医院呼吸与危重症医学科,北京100191

出　　处：《国际呼吸杂志》2024年第6期649-654,共6页International Journal of Respiration

基　　金：北京市科技新星计划交叉合作课题(20220484157);中央级公益性科研院所科研业务项目(2020-PT320-005);北京大学第三医院院队列项目B类(BYSYDL2021013)。

摘　　要：一秒率正常的肺功能受损(PRISm)是一种常见的肺功能障碍,与慢性阻塞性肺疾病、多种合并症及危险因素密切相关。《慢性阻塞性肺疾病全球创议(2024版)》对PRISm进行了扩充修订,PRISm并不总是稳定的表型,随着时间的推移,肺量计检查结果可转变为正常或气流阻塞。因此,早期关注PRISm有助于疾病的预防、早期诊断和干预治疗。本文结合指南从PRISm的概念、研究进展和研究意义等方面对PRISm进行解读。Preserved ratio impaired spirometry(PRISm)is a common pulmonary dysfunction,closely related to COPD,multiple comorbidities,and risk factors.The Global Initiative for Chronic Obstructive Lung Disease(2024 report)provides an expanded revision of PRISm,which is not always a stable phenotype and can transition to both normal and obstructed spirometry over time.Therefore,early attention to PRISm can help in the prevention,early diagnosis,and intervention treatment of the disease.In this paper,a detailed interpretation of the concept of PRISm,the research progress,and the research significance will be carried out.

关 键 词：肺疾病 慢性阻塞性 一秒率正常的肺功能受损 研究进展 研究意义 

分 类 号：R563.9[医药卫生—呼吸系统]