海洋中药多糖的研究进展  

Research progress of the polysaccharides from marine Chinese medicines

作　　者：王永洁 秦玲 范莹 毛文君[3] WANG Yongjie;QIN Ling;FAN Ying;MAO Wenjun(Pharmacy Department,Qingdao Special Servicemen Recuperation Center of PLA Navy,Qingdao 266071,China;First Institute of Oceanography,Ministry of Natural Resource,Qingdao 266061,China;Key Laboratory of Marine Drugs,Ministry of Education,Shandong Provincial Key Laboratory of Glycoscience and Glycoengineering,School of Medicine and Pharmacy,Ocean University of China,Qingdao 266003,China)

机构地区：[1]海军青岛特勤疗养中心药剂科,山东青岛266071 [2]自然资源部第一海洋研究所,山东青岛266061 [3]中国海洋大学海洋药物教育部重点实验室,山东省糖科学与糖工程重点实验室,医药学院,山东青岛266003

出　　处：《中国海洋药物》2024年第3期73-78,共6页Chinese Journal of Marine Drugs

基　　金：山东省重大科技创新工程专项(2018SDKJ0401-3)资助。

摘　　要：我国海洋资源丰富,海洋动植物作为药用资源的历史悠久。随着科学技术的发展,从研究海洋天然产物的角度开发海洋中药资源,为中药资源开发利用提供了新的思路。多糖作为海洋动植物中药的药效物质之一,具有资源丰富和活性广泛的特点。研究发现,海洋中药多糖结构复杂多样,具有抗氧化、免疫调节、抗肿瘤和抗凝血等活性。本文综述了近年来海洋来源的中药多糖的结构和活性研究,为海洋中药资源的深度开发和海洋多糖类药物的研究提供参考。China possesses a plentiful supply of marine resources.The animals and plants from the marine enviroment have a long history as medicinal resources.With the progress of science and technology,the development and utilization of marine Chinese medicine have been provided with new ideas on the basis of the studying marine natural products.Polysaccharides,as one of the medicinal substances in marine Chinese medicine,have the characteristics of abundant resources and extensive activity.Some investigations have found that the polysaccharides from marine Chinese medicine have complex and diverse structures,and exhibit antioxidant,immune regulatory,anti-tumor and anticoagulant activities.This article reviews the achievements in the structure and activity of the polysaccharides from marine Chinese medicine in recent years,and provides a reference for the further development of marine Chinese medicine and the research of marine polysaccharide drugs.

关 键 词：海洋中药 多糖 结构 活性 

分 类 号：R282.77[医药卫生—中药学]