异基因造血干细胞移植后耶氏肺孢子菌肺炎与巨细胞病毒性肺炎CT表现  

CT manifestations of pneumocystis jirovecii pneumonia and cytomegalovirus pneumonia after allogeneic hematopoietic stem cell transplantation

作　　者：程敏[1] 陈皓[1] 孙烨[1] 曹旭阳 洪楠[1] CHENG Min;CHEN Hao;SUN Ye;CAO Xuyang;HONG Nan(Department of Radiology,Peking University People's Hospital,Beijing 100044,China;Department of Radiology,Beijing Fengtai You'anmen Hospital,Beijing 100069,China)

机构地区：[1]北京大学人民医院放射科,北京100044 [2]北京丰台右安门医院放射科,北京100069

出　　处：《中国医学影像技术》2024年第7期1025-1029,共5页Chinese Journal of Medical Imaging Technology

摘　　要：目的比较异基因造血干细胞移植(allo-HSCT)后耶氏肺孢子菌肺炎(PCP)与巨细胞病毒性肺炎(CMVP)的CT表现。方法回顾性分析21例allo-HSCT后PCP(PCP组)及26例CMVP患者(CMVP组),比较其CT表现。结果组间病灶(包括磨玻璃影及结节)分布方式、肺囊肿、病情达最重时间、30天病灶吸收>50%占比、病灶完全吸收占比及首次磨玻璃影病灶总严重程度评分差异均有统计学意义(P均<0.05)。结论allo-HSCT后PCP与CMVP的CT表现相似,但前者磨玻璃影分布范围较广、其内多见肺囊肿而预后较好,后者磨玻璃影分布范围相对较小、而结节多呈弥漫分布且预后较差。Objective To compare CT manifestations of pneumocystis jirovecii pneumonia(PCP)and cytomegalovirus pneumonia(CMVP)after allogeneic hematopoietic stem cell transplantation(allo-HSCT).Methods Totally 21 PCP patients(PCP group)and 26 CMVP patients(CMVP group)after allo-HSCT were retrospectively enrolled,and CT findings were compared between groups.Results Significant differences of distribution patterns of ground glass opacity(GGO)and nodule lesions,lung cysts,the time of condition reached most severe,the proportion of cases with lesions absorption more than 50%within 30 days,of cases with lesions completely absorbed and the first total severity score(TSS)of GGO were found between groups(all P<0.05).Conclusion CT manifestations of PCP and CMVP after allo-HSCT were somehow similar,but GGO distributed widerly,with more lung cysts and better prognosis in the former,while GGO distrubuted relatively limitted with diffuse nodules and poor prognosis in the latter.

关 键 词：肺炎 造血干细胞移植 体层摄影术 X线计算机 

分 类 号：R563.1[医药卫生—呼吸系统] R814.42[医药卫生—内科学]