机构地区:[1]广州医科大学附属中医医院,广东广州510100 [2]深圳市坪山区人民医院,广东深圳518118
出 处:《山西中医药大学学报》2024年第5期530-534,共5页Journal of Shanxi University of Chinese Medicine
基 金:广东省中医药管理局科研项目(20221318)。
摘 要:目的:观察赖氏通元针法治疗脾肾两虚型肾性贫血的临床疗效及对血红蛋白(Hb)、红细胞(RBC)、血细胞比容(HCT)的影响。方法:按照纳入和排除标准筛选符合条件的60例维持血液透析的脾肾两虚型肾性贫血患者,随机分为对照组(31例)、试验组(31例)。两组患者均予基础治疗,对照组予注射用重组人促红细胞生成素,试验组在对照组治疗基础上联合赖氏通元针法针刺百会、中脘、气海、关元、天枢(双)、足三里(双)、太溪(双)、三阴交(双)、心俞(双)、膈俞(双)、肝俞(双)、脾俞(双)、肾俞(双)。每周3次,两组疗程均为4周。4周后观察两组患者中医证候积分及Hb、RBC、HCT水平的变化,评价赖氏通元针法的疗效。结果:研究过程中两组各脱落1例,最终有效病例每组各30例。(1)两组临床疗效比较,差异无统计学意义(P>0.05),但控效率试验组优于对照组,差异有统计学意义(P<0.05)。(2)治疗后两组患者中医证候积分均降低,试验组治疗后中医证候积分低于对照组,治疗前后中医证候积分差值高于对照组,差异均有统计学意义(P<0.01)。(3)治疗后两组患者Hb、RBC、HCT水平均升高,试验组治疗后Hb、RBC、HCT水平及治疗前后Hb、RBC、HCT水平差值均高于对照组,差异均有统计学意义(P<0.05,P<0.01)。结论:赖氏通元针法治疗脾肾两虚型肾性贫血具有较好的临床疗效,值得在临床推广应用。Objective:To observe the clinical efficacy of Lai′s Tongyuan acupuncture on renal anemia with both deficiency of spleen and kidney and its effects on hemoglobin(Hb),erythrocytes(RBC)and hematocrit(HCT).Methods:According to the inclusion and exclusion criteria,60 patients with renal anemia with both deficiency of spleen and kidney who maintained hemodialysis were selected and randomly divided into control group(31 cases)and experimental group(31 cases).The patients in both groups received basic treatment.The patients in the control group were given recombinant human erythropoietin for injection.On the basis of the treatment in the control group,the patients in the experimental group were treated with Lai′s Tongyuan acupuncture method at Baihui,Zhongwan,Qihai,Guanyuan,Tianshu(bilateral),Zusanli(bilateral),Taixi(bilateral),Sanyinjiao(bilateral),Xinshu(bilateral),Geshu(bilateral),Ganshu(bilateral),Pishu(bilateral)and Shenshu(bilateral).The treatment was given 3 times a week for 4 weeks in both groups.After 4 weeks,the TCM syndrome scores and the levels of Hb,RBC and HCT were observed in the two groups,and the therapeutic effect of Lai′s Tongyuan acupuncture was evaluated.Results:During the study,1 case dropped out in each group,and 30 cases were finally effective in each group.(1)There was no statistical significance in clinical efficacy between the two groups(P>0.05),but the control efficiency of the experimental group was better than that of the control group,with statistical significance(P<0.05).(2)After treatment,the TCM syndrome scores of the two groups were decreased;the TCM syndrome scores of the experimental group was lower than that of the control group,the difference of TCM syndrome scores before and after treatment was higher than that of the control group,and the differences were statistically significan(t P<0.01).(3)After treatment,the levels of Hb,RBC and HCT in the two groups increased.The levels of Hb,RBC and HCT after treatment and the differences of Hb,RBC and HCT before and after treatment in
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