妇科茱萸温经包热敷联合盐酸左氧氟沙星片治疗寒湿凝滞型慢性盆腔炎临床研究  

Clinical Study on Hot Compress with Fuke Zhuyu Wenjing Package and Levofloxacin Hydrochloride Tablets for Chronic Pelvic Inflammatory Disease of Cold-Damp Stagnation Type

作　　者：俞栩喆 赵巧萍[1] 吕双 YU Xuzhe;ZHAO Qiaoping;LYU Shuang(Shengzhou Hospital of Traditional Chinese Medicine,Shengzhou Zhejiang 312400,China)

机构地区：[1]嵊州市中医院,浙江嵊州312400

出　　处：《新中医》2024年第12期103-107,共5页New Chinese Medicine

摘　　要：目的:观察妇科茱萸温经包热敷联合盐酸左氧氟沙星片治疗寒湿凝滞型慢性盆腔炎的疗效。方法:回顾性分析96例寒湿凝滞型慢性盆腔炎患者的临床资料,根据治疗方法的不同分为观察组、对照组各48例。对照组给予盐酸左氧氟沙星片治疗,观察组给予妇科茱萸温经包热敷联合盐酸左氧氟沙星片治疗。2组均以14 d为1个疗程,连续治疗2个疗程。治疗前后评定中医证候评分,检测炎症因子指标[白细胞介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)、C-反应蛋白(CRP)]和血液流变学指标[血浆黏度(PV)、红细胞压积(PCV)、红细胞沉降率(ESR)]。比较2组的临床疗效及不良反应发生率。结果:治疗2个疗程后,观察组总有效率高于对照组(P<0.05)。2组中医证候积分均较治疗前下降(P<0.05)。观察组中医证候积分低于对照组(P<0.05)。2组IL-1β、TNF-α、CRP水平均较治疗前下降(P<0.05)。观察组IL-1β、TNF-α、CRP水平均低于对照组(P<0.05)。2组PV、PCV、ESR值均较治疗前下降(P<0.05)。观察组PV、PCV、ESR值均低于对照组(P<0.05)。2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:应用妇科茱萸温经包热敷联合盐酸左氧氟沙星片治疗寒湿凝滞型慢性盆腔炎能提高临床疗效,较单纯使用盐酸左氧氟沙星片治疗能更为有效地缓解患者的临床症状,减轻炎症反应,促进血液循环。Objective:To observe the therapeutic effect of hot compress with Fuke Zhuyu Wenjing Package and Levofloxacin Hydrochloride Tablets on chronic pelvic inflammatory disease of cold-damp stagnation type.Methods:A retrospective analysis was conducted on the clinical data of 96 patients with chronic pelvic inflammatory disease of cold-damp stagnation type.According to different treatment methods,they were divided into the observation group and the control group,with 48 cases in each group.The control group was treated with Levofloxacin Hydrochloride Tablets,the observation group was treated with hot compress with Fuke Zhuyu Wenjing Package combined with Levofloxacin Hydrochloride Tablets.Both groups were treated for two treatment courses,14 days being a course.The traditional Chinese medicine(TCM)syndrome scores were evaluated before and after treatment,and inflammatory factors indicators[interleukin-1β(IL-1β),tumor necrosis factor-α(TNF-α),C-reactive protein(CRP)]and hemorheological indicators[plasma viscosity(PV),hematocrit(PCV),erythrocyte sedimentation rate(ESR)]were detected.The clinical effects and the incidences of adverse reactions in the two groups were compared.Results:After two courses of treatment,the total effective rate in the observation group was higher than that in the control group(P<0.05).The TCM syndrome scores in both groups were decreased when compared with those before treatment(P<0.05).The TCM syndrome scores in the observation group was lower than that in the control group(P<0.05).The levels of IL-1β,TNF-αand CRP in the two groups were decreased when compared with those before treatment(P<0.05),and the levels of IL-1β,TNF-αand CRP in the observation group were lower than those in the control group(P<0.05).The PV,PCV,and ESR levels in both groups were decreased when compared with those before treatment(P<0.05);the PV,PCV,and ESR levels in the observation group were lower than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions betw

关 键 词：慢性盆腔炎 寒湿凝滞证 妇科茱萸温经包 炎症因子 血液流变学 

分 类 号：R711.33[医药卫生—妇产科学]