复方中药制剂青常颗粒对鸡球虫病的防治效果研究  

Prevention and treatment of chicken coccidiosis with compound Chinese herbal preparation Qingchang granules

作　　者：陈润山 徐进 王宁[2] 何斌 邵志勇 夏琴 杨文海 陈夏冰 刘维 曹锐格 段俊 吴利军 CHEN Runshan;XU Jin;WANG Ning;HE Bin;SHAO Zhiyong;XIA Qin;YANG Wenhai;CHEN Xiabing;LIU Wei;CAO Ruige;DUAN Jun;WU Lijun(Fangxian Animal Husbandry and Veterinary Service Center,Fangxian Hubei 442100,China;Yangtze University,Jingzhou Hubei 434023,China;Wuhan Academy of Agricultural Sciences,Wuhan Hubei 430208,China;Shahe Animal Husbandry and Veterinary Service Center of Fangxian,Fangxian Hubei 442100,China;Wuhan Xintianmu Agricultural Technology Development Co.,Ltd.,Wuhan Hubei 430208,China)

机构地区：[1]湖北省房县畜牧兽医服务中心,湖北房县442100 [2]长江大学,湖北荆州434023 [3]武汉市农业科学院,湖北武汉430208 [4]湖北省房县沙河乡畜牧兽医服务中心,湖北房县442102 [5]武汉市鑫天牧农业科技发展有限公司,湖北武汉430208

出　　处：《中兽医医药杂志》2024年第4期26-31,F0002,共7页Journal of Traditional Chinese Veterinary Medicine

基　　金：武汉市农业科学院2024年创新体系科技强基项目(XKCX202402-2)。

摘　　要：探究复方中药制剂青常颗粒对鸡球虫病的防治效果。试验选取180只1日龄健康的海兰灰雏鸡,随机分为健康对照组(A组)、球虫感染组(B组)、青常颗粒低剂量组(C组)、青常颗粒中剂量组(D组)、青常颗粒高剂量组(E组)、化药对照组(F组),每组3个重复,每个重复10只鸡,试验鸡15日龄时人工感染5×10~4个孢子化的柔嫩艾美耳球虫卵囊,感染8 d后将试验鸡剖检,观察并测定雏鸡存活率、相对增重率、盲肠病变值、球虫卵囊值、免疫器官指数和盲肠组织病理变化,通过计算抗球虫指数来评价青常颗粒对鸡球虫病的防治效果。结果表明,青常颗粒高剂量组雏鸡存活率、相对增重率和免疫器官指数显著高于球虫感染组(P<0.05),而球虫卵囊值和盲肠病变值显著低于球虫感染组(P<0.05);青常颗粒低剂量组、中剂量组、高剂量组的ACI分别为125.81、157.22和173.45,盲肠组织病理观察显示青常颗粒低剂量组、中剂量组、高剂量组总体病理变化轻于球虫感染组。结果提示青常颗粒对鸡球虫病具有良好的防治效果。The objective was to explore the preventive and therapeutic effects of compound Chinese herbal preparations Qingchang on chicken coccidiosis.180 healthy 1-day-old Hailan gray chicks were divided into 6 groups which were group A (healthy control),group B (coccidiosis infection),group C (low dose Qingchang granules),group D(medium dose Qingchang granules),group E (high dose Qingchang granules) and group F (chemical control).Each group had 3 replicates,with 10 chicks in each replicate.After orally administration of 5×10~4Eimeria tenella oocysts to all the groups expect the healthy control when the chicks were 15 days old,the survival rate,relative weight gain rate cecal lesion value,oocyst value,immune organ index and cecal pathological changes were measured at 8 day pos infection.The anticoccidial effects of compound Chinese herbal preparations were evaluated by anticoccidial index(ACI).The results showed that the survival rate,relative weight gain rate and immune organ index of high dose groups of Qingchang granules were significantly higher than those of coccidiosis infection group (P<0.05),while the oocyst value and cecal lesion value were significantly lower than those of coccidiosis infection group (P<0.05).The ACI of low dose medium dose and high dose groups of Qingchang granules were 125.81,157.22 and 173.45,respectively.The cecum pathological change observation showed that Qingchang granules groups were lighter than coccidiosis infection group These results indicate that compound Chinese herbal preparation has good preventive and therapeutic effects on chicken coccidiosis.

关 键 词：中药制剂 柔嫩艾美耳球虫 鸡球虫病 抗球虫指数 

分 类 号：S853.7[农业科学—临床兽医学]