“疏肝调神”皮内针干预对阈下抑郁注意力网络的影响:随机对照试验  

Effects of Shugan Tiaoshen intradermal needling intervention on attentional networks in subthreshold depression:a randomized controlled trial

作　　者：邓颖[1,2] 黄申怡 董甸 赵蜜蜜 符文彬 DENG Ying;HUANG Shenyi;DONG Dian;ZHAO Mimi;FU Wenbin(Guangzhou University of CM,Guangzhou 510006,Guangdong Province,China;Second Affiliated Hospital of Guangzhou University of CM,Guangzhou 510006,Guangdong Province,China;Department of TCM,Eighth Affiliated Hospital of Sun Yat-sen University;Clinical Medicine College of Acupuncture-Moxibustion and Rehabilitation,Guangzhou University of CM;Nanchang City Hongdu Hospital of TCM;Guangdong Provincial Hospital of TCM,Guangzhou 510120)

机构地区：[1]广州中医药大学,广东广州510006 [2]广州中医药大学第二附属医院,广东广州510006 [3]中山大学附属第八医院中医科 [4]广州中医药大学针灸康复临床医学院 [5]南昌市洪都中医院 [6]广东省中医院,广州510120

出　　处：《中国针灸》2024年第7期773-778,共6页Chinese Acupuncture & Moxibustion

基　　金：广东省重点领域研发计划项目:2020B1111100007;广东省中医院中医药科学技术研究专项面上项目:K00413。

摘　　要：目的:采用注意力网络测试(ANT)分析“疏肝调神”皮内针方案对阈下抑郁患者注意力网络的影响。方法:将80例阈下抑郁患者随机分为皮内针组(40例)和安慰针组(40例,脱落2例),另纳入43例健康受试者作为正常组。皮内针组予揿针治疗,安慰针组使用安慰揿针,针尖不刺入皮肤,均穴取双侧心俞、肝俞、神堂及耳穴心、肝等两组方案交替。两组均每周治疗2次,共治疗6周。观察两组阈下抑郁患者治疗前、治疗第3周末、治疗后、治疗结束后1个月(随访)9项患者健康状况问卷(PHQ-9)、广泛性焦虑障碍量表(GAD-7)评分,比较两组阈下抑郁患者治疗前后和正常组健康受试者ANT情况。结果:两组阈下抑郁患者治疗第3周末、治疗后及随访时PHQ-9、GAD-7评分均降低(P<0.05),皮内针组PHQ-9、GAD-7评分治疗前后差值大于安慰针组(P<0.01)。治疗前,阈下抑郁组(皮内针组和安慰针组)执行控制网络反应时高于正常组(P<0.05)。与治疗前比较,皮内针组、安慰针组患者治疗后执行控制网络反应时降低(P<0.05),皮内针组治疗后警觉网络反应时升高(P<0.05);皮内针组警觉网络反应时治疗前后差值大于安慰针组(P<0.01)。结论:“疏肝调神”皮内针方案可以有效改善阈下抑郁患者抑郁、焦虑症状,提高警觉网络效率。Objective To analyze the effects of Shugan Tiaoshen(regulating liver and harmonizing spirit)intradermal needling protocol on the attentional networks of patients with subthreshold depression using the attention network test(ANT).Methods Eighty patients with subthreshold depression were randomly divided into an intradermal needling group(40 cases)and a sham needling group(40 cases,2 cases dropped out),with an additional 43 healthy subjects as a normal group.The intradermal needling group received intradermal needling treatment,while the sham needling group received sham intradermal needling,with the needle tip not penetrating the skin.The bilateral Xinshu(BL 15),Ganshu(BL 18),Shentang(BL 44)as well as auricular points Xin(CO15)and Gan(CO12)were selected alternately.Treatments were administered twice a week for a total of 6 weeks in the two groups.The patient health questionnaire-9(PHQ-9)and generalized anxiety disorder(GAD-7)scores were observed before treatment,after 3 weeks of treatment,after treatment,and at 1 month after the end of treatment(follow-up),and the ANT of the two groups of patients with subthreshold depression before and after treatment as well as the normal group of healthy subjects was compared.Results The PHQ-9 and GAD-7 scores of the patients with subthreshold depression were decreased after 3 weeks of treatment,after treatment,and in follow-up in the two groups(P<0.05),the differences in PHQ-9 and GAD-7 scores before and after treatment were greater in the intradermal needling group than those in the sham needling group(P<0.01).Before treatment,the executive control network reaction time of the subthreshold depression group(the intradermal needling group and the sham needling group)was higher than that of the normal group(P<0.05).Compared before treatment,the executive control network reaction time of the patients in the intradermal needling group and the sham needling group was decreased after treatment(P<0.05),and the alerting network reaction time of the intradermal needling group was incre

关 键 词：阈下抑郁 皮内针 疏肝调神 注意力网络 

分 类 号：R246.6[医药卫生—针灸推拿学]