创新慢性呼吸疾病中医疗效评价方法,阐释中医治疗作用机制与物质基础  

Innovating the Effective Evaluation Method for Traditional Chinese Medicine in the Treatment of Chronic Respiratory Diseases,and Explaining the Mechanism and Substance Basis

作　　者：李建生[1,2] 谢洋[1,2] 赵鹏 Jiansheng Li;Yang Xie;Peng Zhao(Co-construction Collaborative Innovation Center for Chinese Medicine and Respiratory Diseases by Henan&Education Ministry of P.R.China/Henan Key Laboratory of Chinese Medicine for Respiratory Disease,HenanUniversityof Chinese Medicine,Zhengzhou 450046;The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000)

机构地区：[1]河南中医药大学呼吸疾病中医药防治省部共建协同创新中心/河南省中医药防治呼吸病重点实验室,郑州450046 [2]河南中医药大学第一附属医院,郑州450000

出　　处：《中国科学基金》2024年第3期469-474,共6页Bulletin of National Natural Science Foundation of China

基　　金：国家重点研发计划项目(2023YFC3502600);国家自然科学基金重点项目(81830116);呼吸疾病中医药防治国家中医药传承创新团队项目(ZYYCXTD-C-202206)的资助。

摘　　要：中医药防治重大慢性呼吸疾病优势明显,如何科学彰显其疗效优势、阐释其作用机制与物质基础,是目前亟需解决的重要科学问题。本文分析了中医疗效评价的现状和问题,结合中医学特点,建议采用国际公认的循证医学方法,完善高级别证据体系,科学诠释中医药疗效;重视病证结合模式下的证候疗效评价,创新临床疗效评价方法技术,使中医疗效评价体系更加客观、标准、规范;基于中医药理论,采用现代科学方法技术,阐释中医药疗效物质与机制的科学内涵,为科学评价中医药疗效提供可靠依据。Traditional Chinese medicine(TCM)has obvious advantages in the prevention and treatment of major chronic respiratory diseases.How to scientifically and objectively demonstrate the advantages of TCM efficacy and explain the mechanism and material basis is an important scientific problem that needs to be solved urgently.This paper analyzes the present situation and problems of the evaluation of the curative effect of TCM,and proposes to adopt the internationally recognized method of evidence-based medicine to perfect the high-level evidence system and scientifically interpret the curative effect of TCM.Attach importance to the evaluation of TCM syndromes curative effect under the mode of combination of disease and syndrome,and innovate the methods and techniques of clinical curative effect evaluation of TCM,to make the evaluation system of TCM more objective,standard and standardized.Based on the theory of TCM,modern scientific methods and techniques are adopted to explain the scientific connotation of the therapeutic substance and mechanism of TCM,to provide a reliable basis for the scientific evaluation of the curative effect of TCM.

关 键 词：呼吸疾病 疗效评价 机制 

分 类 号：R259[医药卫生—中西医结合]