针灸干预卒中后认知障碍的作用机制研究进展  

Research progress on the mechanism of post-stroke cognitive impairment by acupuncture and moxibustion intervention

作　　者：谢亚威 赵永辰[2] 李轶璠 李德需[2] XIE Yawei;ZHAO Yongchen;LI Yifan;LI Dexu(College of Traditional Chinese Medicine,Hebei University,Baoding 071000,China;Affiliated Hospital of Hebei University,Baoding 071000,China)

机构地区：[1]河北大学中医学院,保定071000 [2]河北大学附属医院,保定071000

出　　处：《中华中医药杂志》2024年第7期3571-3574,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：河北省2018年度中医药类科研计划课题(No.2018146)。

摘　　要：卒中后认知障碍(PSCI)是卒中常见并发症。研究表明,针灸能有效减轻其症状,提高认知功能,近年来针灸治疗该病的作用机制也不断发展,通过总结近年文献发现,针灸治疗PSCI的机制为抑制中枢炎症反应、抗氧化应激损伤、调节酶活性、抑制神经细胞凋亡、调控细胞自噬活性水平、改变血管血液流变性等方面,并对目前研究存在的问题进行探讨,以期为临床治疗该病提供更加有效的参考。Post-stroke cognitive impairment(PscI)is a common complication of stroke.According to studies,acupuncture and moxibustion are excellent ways to reduce their symptoms and enhance cognitive performance.In recent years,the mechanism of acupuncture and moxibustion in treating the disease has also been developing.Through summarizing recent literature,it has been found that acupuncture and moxibustion have been found to inhibit central inflammatory reactions,resist oxidative stress injury,regulate enzyme activity,inhibit neuronal apoptosis,regulate the level of autophagy activity,and change vascular and blood rheology in the treatment of PSCI.And the existing problems in current research are explored,in order to provide better and effective references for clinical treatment of this disease.

关 键 词：卒中后认知障碍 针灸 文献 综述 现状 作用机制 

分 类 号：R246.6[医药卫生—针灸推拿学]