针刺加督灸治疗职业性慢性苯中毒效果观察  

Observation on the outcome of occupational chronic benzene poisoning treated with acupuncture combined with Du-Moxibustion

作　　者：郑莹 赖丽丽[1] 邓小峰[1] 樊春月[1] 伍津[1] 区敏 姚淑芳[2] 王海兰[1] ZHENG Ying;LAI Lili;DENG Xiaofeng;FAN Chunyue;WU Jin;OU Min;YAO Shufang;WANG Hailan(Guangdong Province Hospital for Occupational Disease Prevention and Treatment,Guangzhou,Guangdong 510300,China;不详)

机构地区：[1]广东省职业病防治院,广东广州510300 [2]广州新海医院,广东广州510300

出　　处：《中国职业医学》2024年第2期210-213,218,共5页China Occupational Medicine

基　　金：广东省中医药局面上科研项目(20212030)。

摘　　要：目的探讨针刺加督灸(ADM)对职业性慢性苯中毒患者周围血细胞计数和免疫因子水平的影响。方法采用判断抽样方法,选择70例职业性慢性苯中毒(白细胞减少症、中性粒细胞减少症)患者为研究对象,采用随机数表法将其分为对照组和ADM组,每组35例。对照组患者予以升白细胞、对症治疗等西医常规治疗;ADM组患者在对照组的基础上加用ADM治疗,每周1次,连续治疗5周。采集2组患者治疗前后周围血,检测细胞计数和血清免疫因子水平。结果治疗后,2组患者白细胞计数、红细胞计数、淋巴细胞绝对值、中性粒细胞绝对值、血红蛋白水平、血小板计数、免疫球蛋白(Ig)A、IgM、IgG、补体C3和补体C4水平均较同组治疗前有改善(P值均<0.05),且治疗后ADM组患者白细胞计数、IgA、IgM、IgG、补体C3和补体C4水平均高于对照组(P值均<0.05)。结论ADM治疗可提高职业性慢性苯中毒(白细胞减少症、中性粒减少症)患者周围血白细胞水平和体内血清免疫因子水平,有助于提高患者康复效果,可临床推广。Objective To investigate the effects of acupuncture combined with Du-Moxibustion(ADM)on peripheral blood cell count and levels of immune factors in patients with occupational chronic benzene poisoning.Methods A total of 70 patients with occupational chronic benzene poisoning(leukopenia and neutropenia)were selected as the research subjects by judgement sampling method.They were randomly divided into a control group and an ADM group using a random number table method,with 35 cases in each group.Patients in the control group were treated with conventional Western medicine such as leukocyte boosting and symptomatic treatment.While patients in the ADM group were treated with ADM treatment in addition to treatments of the control group,once per week for five consecutive weeks.Peripheral blood samples of patients were collected before and after treatment from both groups,to detect cell counts and serum levels of immune factors.Results The white blood cell count,red blood cell count,absolute lymphocyte count,absolute neutrophil count,platelet count,and levels of hemoglobin,immunoglobulins(Ig)A,IgM,IgG,complement C3 and complement C4 of patients in both groups improved after treatment compared with those before treatment(all P<0.05).The white blood cell count,levels of IgA,IgM,IgG,complement C3 and complement C4 of patients in the ADM group were higher than those in the control group after treatment(all P<0.05).Conclusion ADM treatment can increase peripheral blood white blood cells and serum levels of immune factor in patients with occupational chronic benzene poisoning(leukopenia,neutropenia),which helps improve patient recovery and can be promoted clinically.

关 键 词：职业性慢性苯中毒 白细胞减少症 中性粒减少症 针刺 督灸 血清免疫因子 白细胞计数 

分 类 号：R135.12[医药卫生—劳动卫生]