单纯疱疹病毒脑炎后的抗Ri抗体脑炎1例报告  

Anti-Ri antibody encephalitis secondary to herpes simplex virus encephalitis:a case report

作　　者：刘月 邓晖[1] 郝雅雯 杨斯闵 王旭[1] LIU Yue;DENG Hui;HAO Yawen(Department of Neurology,The First Hospital of Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学白求恩第一医院神经内科,吉林长春130021

出　　处：《中风与神经疾病杂志》2024年第7期642-645,共4页Journal of Apoplexy and Nervous Diseases

基　　金：国家自然科学基金青年科学基金项目(81901083);国家自然科学基金持续资助基金(2022-CXQ-03)。

摘　　要：单纯疱疹病毒脑炎是感染性脑炎中最常见的类型,但其预后较差。部分患者会出现复发或者继发自身免疫性脑炎的发生。本文报告1例单纯疱疹病毒脑炎后继发抗Ri抗体脑炎的病例,以帮助提高临床医生对其的认识,避免发生误诊、漏诊等事件发生。尤其在既往有肿瘤的患者中,副肿瘤综合征相关抗体应予以筛查,早期的诊断及免疫治疗对患者的预后起到重要作用。Herpes simplex virus encephalitis is the most common type of infectious encephalitis with a poor prognosis,and some patients may develop recurrent or secondary autoimmune encephalitis.This article reports a case of anti-Ri antibody encephalitis secondary to herpes simplex virus encephalitis,in order to improve the understanding of this disease among clinicians and avoid misdiagnosis and missed diagnosis.Antibodies associated with paraneoplastic syndrome should be screened for patients with a previous history of tumor,and early diagnosis and immunotherapy play an important role in improving the prognosis of patients.

关 键 词：脑炎 自身免疫性脑炎 单纯疱疹病毒脑炎 抗Ri抗体 

分 类 号：R512.3[医药卫生—内科学]