基于癌毒性质及强弱探析中医分型论治乳腺癌临床思路  

Exploring the Clinical Approach of Treating Breast Cancer in Traditional Chinese Medicine Through Syndrome Differentiation Based on the Nature and Intensity of the Cancer Toxin

作　　者：卓至丽 宋清雅 卢雯平[1] 吴晓晴 崔永佳 张冬妮 常磊 梅荷婷 ZHUO Zhili;SONG Qingya;LU Wenping;WU Xiaoqing;CUI Yongjia;ZHANG Dongni;CHANG Lei;MEI Heting(Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China;Graduate School,Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]中国中医科学院广安门医院,北京100053 [2]北京中医药大学研究生院,北京100029

出　　处：《中国中医药信息杂志》2024年第8期176-181,共6页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：国家中医药管理局中西医结合与少数民族医药司政府购买服务项目任务(ZYZB-2022-798);中央高水平中医医院临床研究和成果转化能力提升项目(HLCMHPP2023037);国家自然科学基金面上项目(81973839)。

摘　　要：癌毒是导致乳腺癌异质性的特异病机。癌毒的性质和毒力的强弱变化决定了乳腺癌异质性的差异变化,其可随时间、空间动态演变,表现为肿瘤的侵袭能力和侵袭特点不一致。原发灶的癌细胞具备靶向特定脏腑转移的“毒性”,癌毒可影响不同分型乳腺癌的转移嗜性。基于癌毒理论的乳腺癌治疗策略强调全程攻伐癌毒,重在辨癌毒强弱和性质,先安未受邪之地,以证为态,识态定靶,以对抗源自肿瘤内异质性的阻力。文章旨在为不同分型乳腺癌的治疗策略提供新的理论基础。Cancer toxin is a specific pathogenesis leading to the heterogeneity of breast cancer.The nature and virulence of the cancer toxin determine the differences in the heterogeneity of breast cancer,which can dynamically evolve over time and space,resulting in varying invasion abilities and characteristics of the tumor.Cancer cells in the primary lesion possess“toxicity”that targets specific organs for metastasis,and cancer toxins can influence the metastatic propensity of different types of breast cancer.Therefore,breast cancer treatment strategies based on the theory of cancer toxins emphasize the continuous eradication of the cancer toxin,focusing on differentiating its strength and nature,protecting unaffected areas first,identifying the state based on symptoms,and targeting accordingly to combat resistance arising from tumor heterogeneity.This article aims to provide a new theoretical basis for the treatment strategies of different types of breast cancer.

关 键 词：乳腺癌 癌毒 分型论治 异质性 临床思路 

分 类 号：R273.79[医药卫生—中西医结合]