眩晕贴联合甲磺酸倍他司汀片治疗痰浊型耳石症复位后残存头晕临床研究  

Clinical Study on the Therapeutic Effect of Vertigo Patch Combined with Betahistine Mesylate Tablets in Treating Residual Dizziness of Phlegm-Turbidity Type Benign Paroxysmal Positional Vertigo After Repositioning

作　　者：陈静雯 李迎华 任绍林 邱英杰 郭锦桥 付晓双 CHEN Jingwen;LI Yinghua;REN Shaolin;QIU Yingjie;GUO Jinqiao;FU Xiaoshuang(Miyun Campus of Beijing University of Chinese Medicine Third Affiliated Hospital,Beijing,China,101500)

机构地区：[1]北京中医药大学第三附属医院密云院区,北京101500

出　　处：《河南中医》2024年第8期1235-1240,共6页Henan Traditional Chinese Medicine

基　　金：北京中医药大学第三附属医院密云院区2023年度院级科研课题项目(KJQ2023-002)。

摘　　要：目的:观察眩晕贴联合甲磺酸倍他司汀片治疗痰浊型耳石症复位后残存头晕的临床疗效。方法:选取2023年4—11月北京中医药大学第三附属医院密云院区眩晕门诊收治的耳石症复位成功后存在残存头晕且辨证为痰浊证的患者100例,采用随机数字表法分为治疗组及对照组,每组50例。两组患者均给予甲磺酸倍他司汀片口服治疗,治疗组另给予眩晕贴贴敷大椎穴治疗,对照组另给予安慰剂制成的药饼贴大椎治疗。比较两组治疗前和治疗3 d、7 d及14 d后的眩晕障碍量表(dizziness handicap inventory,DHI)评分、中医证候积分及残余眩晕程度评分(visuo-analogic scale,VAS)及临床疗效。结果:两组患者DHI总分以及各专项评分、VAS评分、中医证候积分均随时间的延长有所改善,治疗组治疗7 d后、14 d后DHI总分及各专项评分、中医证候积分、VAS评分均明显低于对照组,差异有统计学意义(P<0.05)。治疗组有效率为96%,对照组有效率为86%,治疗组有效率高于对照组,差异有统计学意义(P<0.05)。结论:眩晕贴贴敷大椎联合甲磺酸倍他司汀片可提高痰浊型耳石症患者复位后残存头晕的临床疗效,改善患者症状,提高生活质量。Objective:To observe the clinical efficacy of vertigo patch combined with Betahistine Mesylate Tablets on residual dizziness of phlegm-turbidity type benign paroxysmal positional vertigo(BPPV)after repositioning.Methods:A total of 100 patients with residual dizziness after successful repositioning of BPPV and diagnosed with phlegm-turbidity syndrome who were admitted to the dizziness clinic of Miyun Campus of Beijing University of Chinese Medicine Third Affiliated Hospital,Beijing from April to November 2023 were selected,and divided into the treatment group and the control group according to the random number table method,with 50 cases in each group.Both groups were first given oral treatment with Betahistine Mesylate Tablets.Then the treatment group was also given vertigo patch applied to Dazhui(DU 14),while the control group was additionally given a placebo-made medicine patch applied to Dazhui(DU 14).The dizziness handicap inventory(DHI)scores,TCM syndrome scores,visual analog scale(VAS)scores,before treatment and after 3 days,7 days,and 14 days of treatment,and clinical efficacy were compared between the two groups.Results:Both groups showed improvement in total DHI score and each specific score,VAS score,and TCM syndrome scores over time.The total DHI score and each specific score,TCM syndrome scores,and VAS score of the treatment group were significantly lower than those of the control group 7 days and 14 days after treatment,with statistically significant differences(P<0.05).The effective rate of the treatment group was 96%,while that of the control group was 86%,with a statistically significant difference(P<0.05).Conclusion:Applying the vertigo patch to Dazhui(DU 14)combined with Betahistine Mesylate Tablets can improve the clinical efficacy of residual dizziness in BPPV patients with phlegm-turbidity syndrome after repositioning,enhance their quality of life.

关 键 词：耳石症 残存头晕 痰浊证 眩晕贴 大椎 甲磺酸倍他司汀片 

分 类 号：R255.3[医药卫生—中医内科学]