全球消除疟疾的生物学挑战Ⅲ媒介杀虫剂抗性  

Biological threats to global malaria elimination Ⅲ Vector insecticide resistance

作　　者：朱国鼎[1,2] ZHU Guoding(National Health Commission Key Laboratory of Parasitic Disease Control and Prevention,Jiangsu Provincial Key Laboratory of Parasite and Vector Control Technology,Jiangsu Institute of Parasitic Diseases,Wuxi,Jiangsu 214064,China;Center for Global Health,School of Public Health,Nanjing Medical University,Nanjing,Jiangsu 211166,China)

机构地区：[1]国家卫生健康委员会寄生虫病预防与控制技术重点实验室、江苏省寄生虫与媒介控制技术重点实验室、江苏省血吸虫病防治研究所,江苏无锡214064 [2]南京医科大学公共卫生学院全球健康中心,江苏南京211166

出　　处：《中国血吸虫病防治杂志》2024年第3期243-246,271,共5页Chinese Journal of Schistosomiasis Control

基　　金：国家重点研发计划(2023YFA1801004);国家自然科学基金委员会与比尔及梅琳达·盖茨基金会联合资助项目(82261128002);江苏省“科教能力提升工程”项目(ZDXYS202207)。

摘　　要：传疟媒介杀虫剂抗性问题日益严峻,已成为全球消除疟疾面临的最重要挑战之一。目前,传疟媒介不仅对有机氯、有机磷、氨基甲酸酯和拟除虫菊酯类等传统杀虫剂产生了高度抗性,而且对近年来新使用的新烟碱类和吡咯类杀虫剂亦产生了抗性。本文对当前全球传疟媒介杀虫剂抗性现状和相关抗性治理策略进行了梳理,并就杀虫剂抗性治理中存在的主要问题进行了分析,提出了下一步应对措施,旨在为全球传疟媒介杀虫剂抗性治理提供科学参考,助力全球消除疟疾。The insecticide resistance is becoming increasingly severe in malaria vectors and has become one of the most important threats to global malaria elimination.Currently,malaria vectors not only have developed high resistance to conventional insecticides,including organochlorine,organophosphates,carbamates,and pyrethroids,but also have been resistant to recently used neonicotinoids and pyrrole insecticides.This article describes the current status of global insecticide resistance in malaria vectors and global insecticide resistance management strategies,analyzes the possible major challenges in the insecticide resistance management,and proposes the response actions,so as to provide insights into global insecticide resistance management and contributions to global malaria elimination.

关 键 词：疟疾 消除 传疟媒介 按蚊 杀虫剂抗性 抗性治理 

分 类 号：R531.3[医药卫生—内科学]