硼自由基促进的C—C键形成反应构筑联芳基和苄基羧酸甲酯  

Boryl Radical-Promoted Synthesis of Biaryls and Benzylcarboxylic Acids Methyl Ester via C—C Bond Formation Reactions

作　　者：李文多 魏娜娜 冯楠 Wenduo Li;Na'na Wei;Nan Feng(Gansu Key Laboratory of Efficient Utilization of Oil and Gas Resources in Longdong,College of Petroleum and Chemical Engineering,Longdong University,Qingyang,Gansu 745000;Gansu Key Laboratory of Conservation and Utilization of Biological Resources and Ecological Restoration in Longdong,College of Life Science&Technology,Longdong University,Qingyang,Gansu 745000;College of Petroleum and Chemical Engineering,Longdong University,Qingyang,Gansu 745000)

机构地区：[1]陇东学院石油化工学院甘肃省陇东油气资源高效利用重点实验室,甘肃庆阳745000 [2]陇东学院生命科学与技术学院甘肃省陇东生物资源保护利用与生态修复重点实验室,甘肃庆阳745000 [3]陇东学院石油化工学院,甘肃庆阳745000

出　　处：《有机化学》2024年第6期1853-1861,共9页Chinese Journal of Organic Chemistry

基　　金：甘肃省自然科学基金(No.22JR5RM203);陇东学院博士基金(No.XYBYZK2221,XYBYZK2224);陇东学院青年科技创新基金(No.XYZK2303);甘肃省教育厅创新基金(No.2024A-164)资助项目。

摘　　要：发展了有机光氧化还原催化下,四芳基硼酸酯作为硼基自由基前体构建C—C键的简单方法.该策略不仅可以用于制备对称和不对称的联芳基化合物,而且还可以用于苄醇的直接脱氧羧基化.控制实验和机理研究表明,芳基硼自由基作为可能的反应活性中间体.A facile route for the formation of C—C bonds with tetraarylborates as boryl radical precursors under organophotoredox conditions is developed.This strategy has been verified to be applicable not only for the preparation of symmetrical and unsymmetrical biaryls,but also for direct carboxylation of a range of free benzyl alcohols.Control experiments and mechanism studies indicated that aryl boron radical species is a reactive intermediate.

关 键 词：光氧化还原催化 四芳基硼酸酯 硼基自由基 C一C键形成 联芳基化合物 羧酸 

分 类 号：O621.25[理学—有机化学]