过渡金属催化1,3-共轭二烯基硼化合物合成研究进展  

Research Progress of Transition Metal-Catalyzed Synthesis of 1,3-Conjugated Dienyl Boron Compounds

作　　者：徐光利 韩鸿萍 曹露微 洪思敏 海林悦 崔香 Xu Guangli;Han Hongping;Cao Luwei;Hong Simin;Hai linyue;Cui Xiang(College of Chemistry&Chemical Engineering,Qinghai Normal University,Xining 810000;Academy of Plateau Science and Sustainability,Xining 81000;Qinghai Key Laboratory of Advanced Technology and Application of Environmental Functional Materials,Xining 810016)

机构地区：[1]青海师范大学化学化工学院,西宁810000 [2]高原科学与可持续发展研究院,西宁810000 [3]青海省环境功能材料先进技术与应用重点实验室,西宁810016

出　　处：《有机化学》2024年第5期1480-1493,共14页Chinese Journal of Organic Chemistry

基　　金：青海省自然科学基金(No.2024-ZJ-998);青海师范大学中青年(No.2023QZR017)资助项目。

摘　　要：1,3-二烯基硼化合物在生物活性分子修饰和有机合成中具有重要应用,可以作为有机硼试剂通过Suzuki反应构建新的有机框架,也可以发生Diels-Alder环加成反应来制备硼代环烯烃中间体.目前共轭烯基硼化合物的合成一般是通过过渡金属催化有机金属试剂对炔烃或烯烃的交叉偶联反应、硼酸酯对烯烃的Heck反应、烯炔硼氢化反应或烯炔碳硼化反应实现.以过渡金属催化的不同反应类型为主线,分类对1,3-共轭二烯基硼化合物的合成进行了综述,并对其发展前景予以展望.1,3-Dienyl boron compounds have important applications in the modification of biologically active molecules and organic synthesis.It can be used as an organoboron reagent to construct a new organic framework by Suzuki reaction,and and can also undergo Diels-Alder reaction to prepare boron substituted cycloolefin intermediates.At present,the synthesis of 1,3-conjugated dienyl boron compounds is mainly achieved through the cross-coupling reaction of organometallic reagents to alkynes or olefin catalyzed by transition metals,the Heck reaction of borates to olefin,the hydroboration of alkynes and the carboboration of alkynes.The synthesis of 1,3-conjugated dienyl boron compounds is reviewed by classification based on different reaction types catalyzed by transition metals,and its development prospects are prospected.

关 键 词：过渡金属 催化 1 3-共轭二烯基硼 硼氢化 碳硼化 

分 类 号：O627.31[理学—有机化学]