“和法”与针刺联合西药治疗合并焦虑抑郁的肝胃不和型胃食管反流病临床观察  

Clinical Observation of“Harmony Method”and Acupuncture Combined with Western Medicine in the Treatment of Gastroesophageal Reflux Disease Complicated with Anxiety and Depression

作　　者：赵志幸 郭启涛 史晓花 刘亚莉 李路宝 霍献红 魏勇军[1] 高社光[1] 杨玉巧[1] Zhao Zhixing;Guo Qitao;Shi Xiaohua;Liu Yali;Li Lubao;Huo Xianhong;Wei Yongjun;Gao Sheguang;Yang Yuqiao(Handan Hospital of Traditional Chinese Medicine,Handan 056001,China)

机构地区：[1]邯郸市中医院,河北邯郸056001

出　　处：《亚太传统医药》2024年第7期110-114,共5页Asia-Pacific Traditional Medicine

基　　金：河北省中医药管理局科研计划项目(2019381)。

摘　　要：目的:观察“和法”与针刺联合西药治疗合并焦虑抑郁的肝胃不和型胃食管反流病的临床疗效。方法:将符合纳入标准的93例患者随机分为3组,每组31例。西药组给予奥美拉唑肠溶胶囊、多潘立酮片、氟哌噻吨美利曲辛片口服治疗,中西药组在西药的基础上加“和法”汤剂口服治疗,中西药+针刺组在中西药的基础上加针刺治疗,3组患者疗程均为8周。观察3组患者的临床疗效,比较3组患者治疗前后中医症状积分、胃镜下黏膜积分、焦虑自评量表(SAS)积分以及抑郁自评量表(SDS)积分。结果:3组患者治疗前中医症状积分、胃镜下黏膜积分、SAS积分、SDS积分比较差异无统计学意义(P>0.05),3组患者治疗后中医症状积分、胃镜下黏膜积分、SAS积分、SDS积分均有所下降,3组患者积分比较差异有统计学意义(P<0.05),中西药+针刺组患者积分明显低于其他2组患者。西药组患者总有效率为71.0%,中西药组患者总有效率为80.6%,中西药+针刺组患者总有效率为93.5%,3组患者临床疗效比较差异有统计学意义(P<0.05)。结论:“和法”与针刺联合西药治疗合并焦虑抑郁的肝胃不和型胃食管反流病疗效确切,可有效改善患者胃镜下黏膜糜烂面,提高患者生活质量,促进身心健康。Objective:To observe the clinical effect of the“harmony method”and acupuncture combined with western medicine on gastroesophageal reflux disease combined with anxiety and depression.Methods:93 Patients who met the inclusion criteria were randomly divided into 3 groups,with 31 cases in each group.The western medicine group was given oral treatment with omeprazole enteric capsules,domperidone tablets and floperentixol melitracen tablets,the Chinese and western medicine group was given oral treatment with“harmony method”decoction based on western medicine,and the Chinese and western medicine plus acupuncture group was given oral treatment with acupuncture based on Chinese and western medicine.The course of treatment in the three groups was 8 weeks.The clinical efficacy of the three groups was observed.The TCM symptom scores,gastroscopic mucosal scores,self-rating anxiety scale(SAS)scores,and Self-rating depression scale(SDS)were compared between the three groups before and after treatment.Results:Before treatment,there was no significant difference in TCM symptom score,mucosa score under gastroscope,SAS score and SDS score among the three groups(P>0.05).After treatment,the TCM symptom score,mucosa score under gastroscope,SAS score and SDS score of the three groups decreased,and the difference was statistically significant(P<0.05).The score of Chinese and western medicine plus acupuncture group was significantly lower than that of the other two groups.The total effective rate was 71.0%in the western medicine group,80.6%in the Chinese and western medicine group,and 93.5%in the Chinese and western medicine Plus acupuncture group.There was a statistically significant difference in clinical efficacy among the three groups(P<0.05).Conclusion:The curative effect of the“harmony method”and acupuncture combined with western medicine in the treatment of gastroesophageal reflux disease with anxiety and depression is confirmed,which can effectively improve the mucosal erosion surface of patients under gastroscopy,imp

关 键 词：胃食管反流病 和法 针刺 肝胃不和 西药 焦虑抑郁 

分 类 号：R245[医药卫生—针灸推拿学] R256.3[医药卫生—中医临床基础]