不同强度的抗阻运动对肺癌伴癌因性疲乏患者内分泌激素的调节作用  

The Regulatory Effect of Different Intensities of Resistance Exercise on Endocrine Hormones in Lung Cancer Patients with Cancer-Related Fatigue

作　　者：许海阳[1] 孙巧丹 卢红阳 Xu Haiyang;Sun Qiaodan;Lu Hongyang(Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University,Taizhou Zhejiang 317000,China)

机构地区：[1]浙江省台州医院,浙江台州317000

出　　处：《医疗装备》2024年第12期5-8,共4页Medical Equipment

摘　　要：目的 探讨不同强度的抗阻运动对肺癌伴癌因性疲乏(CRF)患者内分泌激素的调节作用。方法 选择2020年1月至2023年10月于医院就诊的90例肺癌伴CRF患者为研究对象,采用随机数字表法分为试验组和对照组,每组45例。试验组予60%肌肉一次最大重复负荷(1-RM)抗阻运动,对照组予40%1-RM抗阻运动,两组均进行8周抗阻运动。比较两组治疗前及治疗8周后血清甲状腺激素[三碘甲状腺原氨酸(T_(3))和四碘甲状腺原氨酸(T_(4))]和皮质醇(Cor)水平、疲乏症状(MFSI-SF)及临床疗效。结果 治疗8周后,两组血清T_(3)、T_(4)和Cor水平均高于治疗前,且试验组高于对照组,差异有统计学意义(P <0.05);两组MFSI-SF评分均低于治疗前,且试验组低于对照组,差异有统计学意义(P <0.05);试验组临床总有效率高于对照组,差异有统计学意义(P <0.05)。结论 不同强度的抗阻运动均可在一定程度上调整肺癌伴CRF患者内分泌激素、疲乏症状,具有较好的临床疗效,其中60%1-RM的抗阻运动改善效果更明显。Objective To explore the regulatory effect of different intensities of resistance exercise on endocrine hormones in patients with cancer-related fatigue(CRF)in lung cancer.Methods Ninety lung cancer patients with CRF who visited hospitals from January 2020 to October 2023 were selected as the study subjects.They were randomly divided into an experimental group and a control group using a random number table method,with 45 cases in each group.The experimental group received resistance exercise with a maximum repetitive load(1-RM)of 60%of the muscles,while the control group received resistance exercise with 40%of the muscles.The changes in serum thyroid hormone(T_(3) and T_(4))and cortisol(Cor)levels and fatigue symptoms(MFSI-SF)before and after treatment between two groups,as well as the clinical efficacy of the two groups were compared.Results After 8 weeks of treatment,the serum levels of T_(3),T_(4),and Cor in the two groups were higher than before treatment,and the experimental group was higher than the control group,with statistical significance(P<0.05);The MFSI SF scores of the two groups were lower than before treatment,and the experimental group was lower than the control group,with a statistically significant difference(P<0.05);The total clinical effective rate of the experimental group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusions Resistance exercises of different intensities can to some extent adjust endocrine hormones and fatigue in lung cancer patients with CRF It has clinical efficacy,with 60%of 1-RM showing more significant improvement in resistance exercise.

关 键 词：肺癌 癌因性疲乏 抗阻运动 内分泌激素 

分 类 号：R473.73[医药卫生—护理学]