扶阳法治疗肛肠疾病的用方用药分析  

Analysis of the Prescriptions and Medicines Used in the Traditional Chinese Medicine Anorectology to Reinforce Yang

作　　者：魏灿洁 汪昭楚 石荣[2] 王菁[2] Wei Canjie;Wang Zhaochu;Shi Rong;Wang Jing(Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China;Fujian Principal People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou 350004,China)

机构地区：[1]福建中医药大学,福建福州350122 [2]福建中医药大学附属人民医院,福建福州350004

出　　处：《亚太传统医药》2024年第6期129-134,共6页Asia-Pacific Traditional Medicine

基　　金：国家自然科学基金(81973852);国家中医药管理局陈民藩国医大师传承工作室建设项目(国中医药办人教函〔2022〕245号)。

摘　　要：目的:基于数据挖掘的方法探讨扶阳法在治疗中医肛肠科常见疾病上的用药规律和组方特点,为中医肛肠科临床应用扶阳法提供参考。方法:检索中国知网、万方、维普数据库,筛选建库至2023年1月与中医肛肠科临床应用扶阳法相关的文献,将筛选后获得的方药建立数据库,录入古今医案云平台,分析方剂使用频率、药物的使用频次、药物属性、用药模式及组方规律。结果:共纳入符合条件的文献302篇,所涉及肛肠科常见疾病7种:便秘、肠道肿瘤病、直肠脱垂、痔病、肛裂、肛瘘、肛周脓肿。共提取方剂319首,涉及中药217味,累计药物使用频次1 780次。方剂使用频次前5位分别为济川煎加减(29次,9.09%)、补中益气汤加减(19次,5.96%)、补阳还五汤加减(8次,2.51%)、四逆汤加减(7次,2.19%)、附子理中汤加减(7次,2.91%)。高频中药(使用频次≥20次)共21味,排名前5位的分别为当归(79次,24.76%)、白术(76次,23.82%)、肉苁蓉(76次,23.82%)、枳壳(75次,23.51%)和升麻(72次,22.57%)。四气以温性药使用频率最高,其次为平。五味中甘味药使用频率最高,占比45.67%,其次为辛味药。统计药物归属脾经最多,占比45.28%。关联分析显示同现频次最高的药组为白术-当归、当归-白术。结论:中医扶阳法治疗肛肠疾病时,主要以“温阳润肠、益气升提”为基本原则,注重攻补兼施,标本兼顾,为临床用药及新处方研发提供参考。Objective:To explore the medicines pattern and grouping characteristics of the method of reinforcing Yang in TCM anorectal medicine based on data mining method,and to provide some reference for the clinical application of the reinforcing yang method in TCM anorectal medicine.Methods:We have searched the literature related to the clinical application of the the method of reinforcing Yang in TCM anorectal medicine collected by CNKI,Wanfang Data Service Platform,and VIP database from the establishment to January 2023,established a database of the prescriptions obtained after screening,entered them into the ancient and modern medical case cloud platform,analyzed the frequency of prescription using,the frequency of drug using,the The database of prescriptions obtained after screening was established and entered into the ancient and modern medical case cloud platform.Results:A total of 302 eligible documents were included,involving 7 common diseases in anorectology,such as constipation,intestinal tumor disease,rectal prolapse,hemorrhoids,anal fissure,anal fistula,perianal abscess.A total of 319 prescriptions were extracted,involving 217 Chinese herbal medicines,and the cumulative frequency of medicines use was 1780 times.The top five frequently used prescriptions were Ji Chuan Decoction with addition and subtraction(29 times,9.09%),Tonic Zhong Yi Qi Tang with addition and subtraction(19 times,5.96%),Tonic Yang Returning Five Soup with addition and subtraction(8 times,2.51%),Si Wei Tang with addition and subtraction(7 times,2.19%),and Fengshi Rizhong Tang with addition and subtraction(7 times,2.19%).There were 21 high-frequency herbs(used ≥20 times),and the top 5 were Angelica sinensis(79 times,24.76%),Atractylodes macrocephala(76 times,23.82%),Herba Cistanche(76 times,23.82%),Citrus aurantium(75 times,23.51%),and Shengma(72 times,22.57%).The frequency of use of the four qi was highest for warming herbs,followed by Ping.Among the five flavors,sweet drugs were used most frequently,accounting for 45.28%,followed by pung

关 键 词：扶阳法 肛肠疾病 用药规律 数据挖掘 

分 类 号：R266[医药卫生—中医外科学]