IgA肾病预后的影响因素及相关评估模型的研究进展  

Researches progress of influencing factors and relevant evaluation models for prognosis of IgA nephropathy

作　　者：唐天威 叶智明[2] 李锐钊[1,2,3] Tang Tianwei;Ye Zhiming;Li Ruizhao(Guangdong Cardiovascular Institute,Guangdong Provincial People's Hospital,Guangdong Academy of Medical Sciences,Guangzhou 510080,China;Department of Nephrology,Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,Guangzhou 510080,China;Department of Nephrology,Ganzhou Hospital of Guangdong Provincial People's Hospital,Ganzhou Municipal Hospital,Ganzhou 341000,China)

机构地区：[1]广东省心血管病研究所,广东省人民医院,广东省医学科学院,广州510080 [2]广东省人民医院肾内科,南方医科大学附属广东省人民医院(广东省医学科学院),广州510080 [3]广东省人民医院赣州医院(赣州市立医院)肾内科,赣州341000

出　　处：《中华肾脏病杂志》2024年第6期499-505,共7页Chinese Journal of Nephrology

基　　金：广东省基础与应用基础研究项目(2024A1515010424);广东省人民医院登峰计划(KJ012019440);广东省科技厅项目:粤港慢性肾病免疫与遗传研究联合实验室(2019B121205005);广州市科技基础与应用基础研究项目(202102080608)。

摘　　要：IgA肾病(IgA nephropathy,IgAN)是最常见的原发性肾小球疾病,也是肾脏病患者进展至终末期肾病的主要原因。多项临床、病理、人口学指标及近年来研究者们发现的新型指标在IgAN预后评估中扮演着重要角色。综合多项指标建立预后评估模型来早期识别疾病进展风险高的患者具有重要临床意义。该文综述了IgAN患者预后的影响因素及相关评估模型的研究进展。IgA nephropathy(IgAN)is the most common primary glomerular disease and main reason of progression to end‐stage renal disease in patients with kidney diseases.Various clinical,pathological,demographic and new factors discovered by researchers in recent years play important roles in the prognosis assessment of IgAN.Furthermore,developing prognostic evaluation models based on several different factors to identify patients at high risk of progression in the early disease stage is clinically significant.This article reviews the researches progress of influencing factors and relevant evaluation models for prognosis of IgAN.

关 键 词：肾小球肾炎 IgA 预后 危险因素 评估模型 

分 类 号：R692[医药卫生—泌尿科学]