晚发型重度子痫前期患者ST-T段改变与不良妊娠结局的关系  

The relationship between ST-T segment changes and adverse pregnancy outcomes in patients with late onset severe preeclampsia

作　　者：崔婷婷 任敏 CUI Tingting;REN Min(Electrocardiogram Room,Shanghai Key Laboratory of Maternal Fetal Medicine,Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology,Shanghai First Maternity and Infant Hospital,School of Medicine,Tongji University,Shanghai 200092,China;Department of Ultrasound,Shanghai Key Laboratory of Maternal Fetal Medicine,Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology,Shanghai First Maternity and Infant Hospital,School of Medicine,Tongji University,Shanghai 200092,China)

机构地区：[1]同济大学附属第一妇婴保健院心电图室,上海200092 [2]同济大学附属第一妇婴保健院超声科,上海200092

出　　处：《中国优生与遗传杂志》2024年第5期934-941,共8页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨晚发型重度子痫前期(LOSP)患者ST-T段改变与不良妊娠结局之间的关系。方法选取2020年5月至2023年5月期间在同济大学附属第一妇婴保健院产科住院分娩的100例LOSP患者作为观察组,另选取同期健康孕妇100人作为对照组。比较两组患者的临床资料和不良妊娠结局的相关分布情况;探讨ST-T段改变与LOSP患者不良妊娠结局的相关性;绘制ST-T段改变与不良妊娠结局发生的概率曲线图;分析导致不良妊娠结局的危险因素。结果两组患者的年龄、收缩压(SBP)、舒张压(DBP)、子痫前期史、孕前超重肥胖、高血压史、视线模糊状况、长期服用叶酸史、蛋白尿指标检测、近期情绪状况及ST-T段改变均存在显著性差异。观察组的所有不良妊娠结局均显著高于对照组。ST-T段改变与LOSP患者不良妊娠结局风险呈正相关,且不同的ST-T段改变值均有相对应的不良妊娠结局的发生概率。年龄、子痫前期史、孕前超重肥胖、高血压史、视线模糊状况、长期服用叶酸史、蛋白尿指标检测、近期情绪状况、ST-T段改变均是影响LOSP患者出现不良妊娠结局的独立影响因素,且路径系数差异均有统计学意义。结论ST-T段改变和LOSP患者不良妊娠结局风险呈正相关,ST-T段改变可以使LOSP患者发生不良妊娠结局的风险增加,且不同的ST-T段改变值均有相对应的不良妊娠结局发生概率。临床治疗中应重视LOSP患者心电图ST-T段的变化,从而尽早调整治疗方案,避免不良妊娠事件的发生。Objective Explore the relationship between ST-T segment changes and adverse pregnancy outcomes in patients with late onset severe preeclampsia. Methods Select 100 LOSP patients who were hospitalized and delivered in the obstetrics department of Tongji University Affiliated First Maternity and Infant Hospital from May 2020 to May 2023 as an observation group, and select 100 healthy pregnant women in the same period as the control group. Compare the clinical data and distribution of adverse pregnancy outcomes between two groups of patients. Exploring the correlation between ST-T segment changes in electrocardiogram and adverse pregnancy outcomes in LOSP patients. Plot the probability curve of ST-T segment changes and adverse pregnancy outcomes. Analyzing the risk factors leading to adverse pregnancy outcomes. Results There were significant differences in age, systolic blood pressure(SBP), diastolic blood pressure(DBP), history of preeclampsia, pre pregnancy overweight and obesity, history of hypertension, blurred vision, long-term use of folic acid, proteinuria index detection,recent emotional status, and ST-T segment changes between the two groups. All adverse pregnancy outcomes of the observation group were significantly higher than those of the control group. There is a positive correlation between ST-T segment changes and the risk of adverse pregnancy outcomes in LOSP patients, and different ST-T segment changes have corresponding probabilities of adverse pregnancy outcomes. Age, history of preeclampsia, pre pregnancy overweight and obesity, history of hypertension, blurred vision, long-term use of folic acid, proteinuria index testing, recent emotional status, ST-T segment changes are all independent influencing factors that affect the adverse pregnancy outcomes of LOSP patients, and the differences in path coefficients are statistically significant. Conclusion There is a positive correlation between ST-T segment changes and the risk of adverse pregnancy outcomes in LOSP patients. ST-T segment changes can incr

关 键 词：晚发型重度子痫前期 ST-T段改变 不良妊娠结局 

分 类 号：R714.244[医药卫生—妇产科学]