450 nm蓝激光汽化术治疗高危前列腺增生患者临床疗效评价  

Clinical efficacy evaluation of 45Onm blue laser vaporization in the treatment of high-risk patients with benign prostatic hyperplasia

作　　者：张栋邦 胡森[1] 刘炜[1] 颜学栋 谢秀娟 Zhang Dongbang;Hu Sen;Liu Wei;Yan Xuedong;Xie Xiujuan(Department of Urology,Qinghai Red Cross Hospital,Xining 810000,China)

机构地区：[1]青海红十字医院泌尿外科,西宁810000

出　　处：《微创泌尿外科杂志》2024年第3期183-187,共5页Journal of Minimally Invasive Urology

基　　金：2022-2023年青海省卫健委指导性计划课题(2021-wjzdx-63)。

摘　　要：目的:450 nm蓝激光半导体治疗机行经尿道蓝激光汽化术治疗高危前列腺增生(BPH)患者临床疗效评价。方法:纳入青海红十字医院泌尿外科2023年1月至9月BPH患者80例,随机数表法分为研究组和对照组,每组40例。研究组采用经尿道蓝激光汽化术,对照组采用经尿道前列腺电切术(TURP)。对比两组患者手术时间、术后膀胱持续冲洗及导尿管留置时间、术中术后血红蛋白下降值,下床活动时间、前列腺症状改善及并发症发生情况。结果:80例BPH患者均顺利完成手术,TURP组8例患者术中行膀胱造瘘术,研究组术中均未行膀胱造瘘术,研究组较对照组手术耗时短、出血量少、术后膀胱冲洗及导尿管留置时间短、下床活动时间早(P<0.05)。两组患者与术前比较IPSS、PRV均明显下降、Qmax显著升高(P<0.05),术后两组患者组间比较IPSS、PRV、Qmax无显著性差异(P>0.05)。总体并发症发生率低于对照组(P<0.05)结论:经尿道450 nm蓝激光汽化术治疗BPH止血高效、手术耗时短、术中膀胱造瘘率低、并发症少,可有效缩短膀胱冲洗及导尿管留置时间,术后排尿良好,治疗高风险性BPH具有一定的优势性。Objective:To assess the clinical efficacy of transurethral blue laser vaporization using a 450 nm blue laser semiconductor therapy unit in the treatment of high-risk prostatic hyperplasia(BPH).Methods:A total of 80 BPH patients were enrolled from January to September 2023 at the Department of Urology,Qinghai Red Cross Hospital.They were randomly divided into a study group and a control group,with 40 cases in each group.The study group underwent transurethral blue laser vaporization while the control group underwent transurethral resection of prostate(TURP).The two groups were compared for operative time,postoperative bladder irrigation and catheter indwelling time,intraoperative and postoperative hemoglobin decline,time to getout of bed after surgery,improvement in prostatic symptoms and complications.Results:All 8o BPH patients successfully completed the operation.Eight patients in the TURP group required cystostomy during surgery,whereas no cystostomies were performed in the study group.Compared to the control group,the study group had shorter operative times,less bleeding volume,shorter postoperative bladder irrigation and catheter indwelling time,and earlier time to get out of bed(P<0.05).Both groups showed significant decreases in IPSS and PRV scores as well as significant increases in Qmax values after surgery compared to pre-surgery levels(P<0.05),but there was no significant difference between the two groups regarding IPSS scores,PRV scores or Qmax values after surgery(P>0.05).The overall complication rate was lower than that of the control group(P<0.05).Conclusion:Transurethral blue laser vaporization using a 450 nm blue laser is highly effective for treating BPH with advantages such as efficient hemostasis capability,shorter operative times,low incidence of intraoperative bladder fistula,fewer complications,It effectively reduces bladder irrigation and cathe terization time,promotes good postoperative voiding,and demonstrates certain advantages in treating high-risk BPH cases.

关 键 词：高风险 前列腺增生 蓝激光 疗效 

分 类 号：R697.3[医药卫生—泌尿科学]