益气活血法抗肝纤维化作用机制的研究概况  

Research Overview of Anti-hepatic Fibrosis Mechanism of Yiqi Huoxue Method

作　　者：干佳岑 汪静 彭孟云 张玉蓉 GAN Jia-cen;WANG Jing;PENG Meng-yun;ZHANG Yu-rong(School of Integrated Traditional Chinese and Western Medicine,Southwest Medical University,Luzhou 646000,Sichuan,China;Department of Hepatobiliary Diseases,Affiliated Hospital of Traditional Chinese Medicine,Southwest Medical University,Luzhou 646000,Sichuan,China)

机构地区：[1]西南医科大学中西医结合学院,四川泸州646000 [2]西南医科大学附属中医医院肝胆病科,四川泸州646000

出　　处：《医学信息》2024年第15期177-180,共4页Journal of Medical Information

基　　金：泸州市科技计划项目(编号:2022-JYJ-142)。

摘　　要：肝纤维化是慢性肝病发展为肝硬化或原发性肝癌的关键,减轻或逆转肝纤维化成为近年研究热点。中医药在抗肝纤维化方面具有调控肝星状细胞、平衡细胞外基质、抑制上皮间质转化等作用,本文就中医对肝纤维化的认识、病因病机,以及对近年来中医益气活血法治疗肝纤维化的研究概况进行综述,以期为临床应用及后续研究提供支持及依据。Liver fibrosis is the key to the development of chronic liver disease into cirrhosis or primary liver cancer.Reducing or reversing liver fibrosis has become a research hotspot in recent years.Traditional Chinese medicine has the effects of regulating hepatic stellate cells,balancing extracellular matrix and inhibiting epithelial-mesenchymal transition in anti-hepatic fibrosis.This paper reviews the understanding,etiology and pathogenesis of liver fibrosis in traditional Chinese medicine,as well as the research progress of Yiqi Huoxue method in the treatment of liver fibrosis in recent years,in order to provide support and basis for clinical application and follow-up research.

关 键 词：肝纤维化 益气活血法 气虚血瘀 肝星状细胞 细胞外基质 

分 类 号：R512.62[医药卫生—内科学] R575.2[医药卫生—临床医学]