不同剂量麦粒灸对寒湿凝滞型原发性痛经患者子宫动脉血流影响的比较研究  

Comparative study of different dosages of grain-sized moxibustion on uterine artery blood flow in patients with cold and dampness primary dysmenorrhea

作　　者：刘今 刘君 王雪松 李旭欣 林杪 刘俊亚 张细芬 高渊博 路广通 佘延芬 LIU Jin;LIU Jun;WANG Xue-song;LI Xu-xin;LIN Miao;LIU Jun-ya;ZHANG Xi-fen;GAO Yuan-bo;LU Guangtong;SHE Yan-fen(College of Acupuncture-Moxibustion and Massage,Hebei University of Chinese Medicine,Shijiazhuang 050091,China;Hebei Province International Joint Research Center for Advantageous Diseases of Acupuncture and Moxibustion,Shijiazhuang 050200)

机构地区：[1]河北中医药大学针灸推拿学院,石家庄050091 [2]河北省中医针灸优势病症国际联合研究中心,石家庄050200

出　　处：《针刺研究》2024年第7期760-766,共7页Acupuncture Research

基　　金：国家自然科学基金面上项目(No.81973755);国家重点研发计划项目(No.2022YFC3500601);河北省中医药管理局项目(No.2022091)。

摘　　要：目的:观察不同剂量麦粒灸对寒湿凝滞型原发性痛经(PD)患者子宫动脉血流影响的差异。方法:将60例PD患者随机分3壮组、6壮组和9壮组,每组20例。3组均选取三阴交、地机、血海进行治疗,分别采用3壮、6壮和9壮3种不同剂量的麦粒灸,月经来潮前7 d开始治疗3次,共治疗3个月经周期。治疗前后记录患者子宫动脉血流参数指标搏动指数(PI)、阻力指数(RI)、血流比值(S/D);评价治疗前1个月、治疗第1、2、3个月经周期及治疗结束后第1个月经周期的视觉模拟量尺(VAS)评分、Cox痛经症状量表严重程度(CMSS-S)及持续时间(CMSS-T)积分。结果:治疗后9壮组患者的子宫动脉血流PI、RI、S/D值低于本组治疗前及同时点的3壮组和6壮组(P<0.05)。3壮组在第1周期和第2周期VAS评分低于治疗前(P<0.05);6壮组和9壮组各观察时点VAS评分均低于本组治疗前(P<0.05),在治疗第3周期和随访期低于3壮组(P<0.05);9壮组的VAS评分在随访期低于6壮组(P<0.05)。9壮组在治疗第1周期CMSS-T积分较治疗前降低(P<0.05),6壮组、9壮组在治疗第2、3周期及随访期的CMSS-T积分较治疗前降低(P<0.05),6壮组和9壮组的CMSS-T积分在第3周期和随访期低于3壮组(P<0.05),9壮组的CMSS-T积分在随访期低于6壮组(P<0.05);6壮组、9壮组在治疗第2、3周期及随访期CMSS-S积分较治疗前降低(P<0.05),6壮组和9壮组在第3周期和随访期的CMSS-S积分低于3壮组(P<0.05),9壮组的CMSS-S积分在随访期低于6壮组(P<0.05)。结论:麦粒灸治疗原发性痛经具有量效关系,麦粒灸9壮较6壮、3壮在改善PD患者的子宫动脉血流指标和减轻痛经症状等方面更有优势。Objective To observe the differences in the effects of different dosages of grain-sized moxibustion on uterine artery blood flow in patients with cold and dampness primary dysmenorrhea(PD).Methods A total of 60 patients with PD were randomly divided into 3 groups with 20 cases in each group.Acupoints Sanyinjiao(SP6),Diji(SP8)and Xuehai(SP10)were selected in all the 3 groups,and different dosages of grain-sized moxibustion were used(3 moxa cones,6 moxa cones,9 moxa cones)respectively.Treatment started 7 days before menstruation for 3 times,lasting for a total of 3 menstrual cycles.The values of uterine artery blood flow parameters including pulsatility index(PI),resistance index(RI),and systolic/diastolic ratio(S/D)were recorded before and after treatment.The visual analog scale(VAS)score and cox menstrual symptom scale(CMSS)score(including severity[CMSS-S]and time of duration[CMSS-T])were evaluated before treatment,at the end of each menstrual cycle,and one menstrual cycle after treatment.Results The values of uterine artery blood flow parameters(PI,RI,S/D)after treatment in the 9 moxa cones group were lower than those before treatment,as well as lower than those in the 3 and 6 moxa cones groups after treatment(P<0.05).The VAS scores of the 3 moxa cones group were lower than those before treatment in the first and second cycle(P<0.05).The VAS scores of the 6 and 9 moxa cones groups were lower than those before treatment at each observation point(P<0.05),and were lower than those of the 3 moxa cones group in the third cycle of treatment and follow-up period(P<0.05).And the VAS score of the 9 moxa cones group was lower than that of the 6 moxa cones group during the follow-up period(P<0.05).Compared with the scores before treatment,the CMSS-T scores at each observation point after treatment were lower in the 9 moxa cones group(P<0.05);the CMSS-T scores in the second and third cycle after treatment,and follow-up period were lower in the 6 moxa cones group(P<0.05),with the CMSS-S scores in the second and third cycle a

关 键 词：原发性痛经 艾灸量 寒湿凝滞 子宫动脉血流 

分 类 号：R246.3[医药卫生—针灸推拿学]