间苯三酚辅助干预在子宫内膜息肉患者宫腔镜治疗中的应用效果  

Application effect of phloroglucinol assisted intervention in hysteroscopic treatment of patients with endometrial polyps

作　　者：廖露 黄丽 付兰兰[1] Liao Lu;Huang Li;Fu Lan-lan(Department of Obstetrics and Gynecology,The People's Hospital of Shicheng,Ganzhou 342700,Jiangxi,China)

机构地区：[1]石城县人民医院妇科产科,江西赣州342700

出　　处：《四川生理科学杂志》2024年第7期1467-1469,共3页

基　　金：赣州市指导性科技计划(编号:ZSF2023ZSF617)。

摘　　要：目的:探究间苯三酚辅助干预在子宫内膜息肉患者宫腔镜治疗中的应用效果。方法:根据给药不同将石城县人民医院自2020年10月至2023年10月收治的114例需行宫腔镜下子宫内膜息肉切除术患者分为观察组(术前30 min静脉滴注间苯三酚注射液)和对照组(术前8 h用米索前列醇),各57例;比较完成手术全程时间、术中出血量、宫腔镜检查术持续时间,采用视觉模拟评分法(Visual analogue scale,VAS)评估疼痛程度;记录通过最大扩宫器号数和扩宫时间;观察记录不良反应、人工流产综合征(Reaction of artificial abortion syndrome,RAAS)发生率;比较患者住院时间、术前和术后1 m的月经量、月经持续时间以及子宫内膜厚度。结果:观察组手术时间、术中出血量、宫腔镜检查术持续时间、VAS评分、无阻力可通过最大号扩宫器、需要扩宫例数、扩宫时间、RAAS发生率均显著更低(P<0.05),两组患者住院时间、月经量、月经持续时间、子宫内膜厚度、不良反应均无显著性差异(P>0.05)。结论:将间苯三酚辅助干预宫腔镜治疗的子宫内膜息肉患者能有效改善手术一般情况,提高软化宫颈效果,但对预后的影响较小。Objective:To explore the application effect of phloroglucinol-assisted intervention in the hysteroscopic treatment of patients with endometrial polyps.Methods:A total of 114 patients who underwent hysteroscopic endometrial polypectomy at Shicheng County People's Hospital from October 2020 to October 2023 were divided into an observation group(intravenous infusion of phloroglucinol injection 30 minutes before surgery)and a control group(using misoprostol 8 hours before surgery)based on different administration methods,with 57 patients in each group;The completion time of the entire surgery,intraoperative bleeding volume,and duration of hysteroscopy were compared,and the degree of pain was evaluated using Visual Analog Scale(VAS).The maximum number of dilation devices and dilation time passed and the incidence of adverse reactions and induced abortion syndrome(RAAS)were recorded.The length of hospital stay,preoperative and postoperative menstrual flow,menstrual duration,and endometrial thickness of patients were compared.Results:Operation time,intraoperative blood loss,duration of hysteroscopy,VAS score,size of the dilators that freely passed through the cervix,number of cases requiring dilation of the cervix,time for dilation of the cervix and the incidence rate of RAAS in the observation group were significantly shorter,less and lower(P<0.05).There was no significant difference in the length of hospital stay,menstrual volume,duration of menstruation,endometrial thickness,or adverse reactions between the two groups(P>0.05).Conclusion:Applying phloroglucinol-assisted intervention in the hysteroscopic treatment of patients with endometrial polyps can effectively improve general surgical conditions and enhance the cervical softening effect,with little influence on the prognosis.

关 键 词：子宫内膜息肉 间苯三酚 宫腔镜 

分 类 号：R713.4[医药卫生—妇产科学]