下肢骨折患者小剂量轻比重腰-硬联合麻醉前应用布托啡诺的超前镇痛效果观察  

Observation on the pre-analgesic effect of butorphanol in patients with lower extremity fracture before low dose and light weight combined lumbo-epidural anesthesia

作　　者：洪定剑 黄俊 熊涛 Hong Ding-jian;Huang Jun;Xiong Tao(Department of Anesthesiology,Guangxin District People's Hospital,Shangrao 334100,Jiangxi,China;Department of Traumatic Joint Orthopedics,Guangxin District People's Hospital,Shangrao 334100,Jiangxi,China)

机构地区：[1]广信区人民医院麻醉科,江西上饶334100 [2]广信区人民医院创伤关节骨科,江西上饶334100

出　　处：《四川生理科学杂志》2024年第7期1567-1569,共3页

摘　　要：目的:探讨分析下肢骨折患者小剂量轻比重腰-硬联合麻醉前应用布托啡诺的超前镇痛效果观察。方法:选取2022年2月-2023年12月我院收治的行小剂量轻比重腰-硬联合麻醉下肢骨折患者60例,根据麻醉前是否使用布托啡诺镇静药将纳入对象分为未使用组,使用组(给予布托啡诺的超前镇痛),每组患者各30例,比较两组患者不同时间点镇静效果和疼痛评分变化、不良反应发生率。结果:麻醉后5 min(T2)、15 min(T3)、30 min(T4)、以及手术完毕后(T5)使用组的镇静评分较未使用组升高,差异有统计学意义(P<0.05);术后4 h、术后8 h、术后12 h、术后24 h,使用组疼痛评分较未使用组降低,差异有统计学意义(P<0.05);未使用组和使用组的不良反应发生率为10.00%,36.67%,二者相比,使用组的不良反应发生率降低,差异有统计学意义(P<0.05)。结论:下肢骨折患者小剂量轻比重腰-硬联合麻醉前应用布托啡诺的超前镇痛能减少患者的疼痛程度,提高镇静效果,并减少其不良反应。Objective:To investigate and analyze the pre-analgesic effect of butorphanol on patients with lower extremity fracture before low dose light weight combined lumbo-epidural anesthesia.How:A total of 60 patients with lower extremity fracture undergoing low-dose light-weight lumbago and epidural anesthesia admitted to our hospital from February 2022 to December 2023 were selected.According to whether butorphanol was used as a sedative before anesthesia,the included subjects were divided into the non-use group and the use group(pre-analgesia with butorphanol),with 30 patients in each group.The sedation effect,pain score changes and the incidence of adverse reactions were compared between the two groups at different time points.Results:The sedation scores of 5 minutes(T2),15 minutes(T3),30 minutes(T4)after anesthesia and T5 after surgery were higher than those of the non-use group,and the difference was statistically significant(P<0.05).At 4 hours,8 hours,12 hours and 24 hours after surgery,the pain score of the treatment group was lower than that of the non-treatment group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the non-use group and the use group was 10.00% and 36.67%,and the incidence of adverse reactions in the use group was lower than that in the two groups,and the difference was statistically significant(P<0.05).Conclusion:Preemptive analgesia of butorphanol before low dose and light weight combined lumbo-epidural anesthesia in patients with lower extremity fracture can reduce pain degree,improve sedation effect and reduce adverse reactions.

关 键 词：下肢骨折 小剂量轻比重腰-硬联合麻醉 布托啡诺 超前镇痛 

分 类 号：R614[医药卫生—麻醉学]