加强型移动生物安全二级实验室通风系统研究  

Development of ventilation system for enhanced mobile biosafety level-2 laboratory

作　　者：夏建桥 欧阳康 李海洋 XIA Jian-qiao;OU-YANG Kang;LI Hai-yang(Zhenjiang Kangfei Automobile Manufacturing Co.,Ltd.,Zhenjiang 212132,Jiangsu Province,China)

机构地区：[1]镇江康飞汽车制造股份有限公司,江苏镇江212132

出　　处：《医疗卫生装备》2024年第7期29-34,共6页Chinese Medical Equipment Journal

摘　　要：目的:研究加强型移动生物安全二级实验室(以下简称“移动P2+实验室”)的通风系统,以对实验间内部的气溶胶扩散进行有效控制。方法:移动P2+实验室的通风系统采用全新风通风设计,送风为3级过滤,采用定风量控制;排风为1级高效过滤,采用变风量控制,其中缓冲间设有高效过滤排风口,实验间设有风口型排风高效过滤装置。缓冲间通风采用上送上排的布局,送、排风高效集成在吊顶内;实验间通风采用侧上送风、侧下排风的方式。为验证通风系统设计的可行性,采用计算流体力学(computational fluid dynamics,CFD)软件对0°、30°、45°、60°、90°送风角度下的气流组织、温度场和速度场进行分析,并模拟不同送风角度下的实验间气溶胶浓度分布情况,以确定最佳送风角度。结果:经气流组织、温度场、速度场及气溶胶扩散控制能力的综合比较,移动P2+实验室通风系统以60°送风最佳,且检测结果表明该送风角度下的换气次数、静压差、温湿度、洁净度以及气流方向等核心指标均满足GB 27421—2015《移动式实验室生物安全要求》和T/CESC 662—2020《医学生物安全二级实验室建筑技术标准》的要求。结论:在进行移动P2+实验室通风系统设计时,除了要考虑各送、排风口位置和设备设施布局因素,还应选择合适的送风角度,以提升防护区的生物安全性。Objective To develop a ventilation system for the enhaned mobile biosafety level-2(BSL-2)laboratory to control the dispersed aerosol within the laboratory effectively.Methods A ventilation system for the enhanced mobile biosafety level-2 laboratory was designed with the concept of full fresh air ventilation,which realized air supply with 3-stage filtration and constant air volume control,and air exhaust with 1-stage high-efficiency filtration and variable air volume control.The buffer room had the layout of upside air supply and upside exhaust,with the air supply and exhaust equipment integrated into the ceiling;the experimental room had the layout of diagonally upside air supply and diagonally downside exhaust.Computa-tional fluid dynamics(CFD)software was used to analyze the airflow organization,temperature field and velocity field at 0°,30°,45°,60°and 90°air supply angles in order to verify the feasibility of the ventilation system design,and the distributions of aerosol concentration in the experimental room at different air supply angles were simulated to determine the optimal air supply angle.Results Investigations in terms of airflow organization,temperature field,velocity field and aerosol dispersion control showed in case of 60°air supply angel the enhanced mobile BSL-2 laboratory behaved the best and its core indexes all met the requirements of GB 27421—2015 Mobile laboratories—General requirements for biosafety and T/CESC 662—2020 Architectural technical standard for BSL-2 laboratory in medical facilities including the number of air changes,static pressure difference,temperature and humidity,cleanliness and airflow direction.Conclusion Considerations have to be taken on the locations of supply and exhaust outlets,the facility layout and air supply angle when the enhanced mobile BSL-2 laboratory is designed so as to enhance the biosafety of the protective area.[Chinese Medical Equipment Journal,2024,45(7):29-34]

关 键 词：加强型移动生物安全二级实验室 移动生物安全二级实验室 通风系统 送风角度 生物安全 

分 类 号：R318[医药卫生—生物医学工程] R197.39[医药卫生—基础医学]