肿瘤恶病质患者非药物营养管理的最佳证据总结  

Summary of the best evidence for non-pharmacological nutritional management in patients with cancer cachexia

作　　者：席祖洋 魏永婷[1,2] 倪福 范雨晴 Xi Zuyang;Wei Yongting;Ni Fu;Fan Yuqing(Center of Clinical Nur-sing Research,China Three Gorges University,Yichang 443003,China)

机构地区：[1]三峡大学临床护理研究中心,湖北宜昌443003 [2]三峡大学第一临床医学院/宜昌市中心人民医院护理部 [3]三峡大学健康医学院

出　　处：《护理学杂志》2024年第13期106-110,115,共6页Journal of Nursing Science

基　　金：三峡大学重点实验室“肿瘤微环境与免疫治疗”护理科研开放基金(2022KZL1-01)。

摘　　要：目的全面检索并总结国内外肿瘤恶病质患者非药物营养管理的相关最佳循证证据,以期为临床护理实践提供参考。方法按照6S证据模型,系统检索国内外数据库及网站关于肿瘤恶病质患者非药物营养管理的证据,检索时限为建库至2023年9月,对纳入文献进行质量评价,并对证据进行提取、评价、整合,形成最佳证据。结果共纳入文献19篇,包括指南8篇、临床决策2篇、临床路径1篇、立场文件2篇、系统评价3篇、证据总结1篇、专家共识2篇,最终从肿瘤恶病质的评估与诊断、多学科团队及管理目标、营养支持3个方面提取汇总了22条证据。结论肿瘤恶病质患者非药物营养管理的最佳证据可为临床肿瘤恶病质患者开展营养干预提供决策依据,建议临床医护人员结合具体临床情境、患者意愿进行证据转化。Objective To comprehensively search and summarize the evidence for non-pharmacological nutrition management in patients with cancer cachexia,and to provide reference for clinical nursing practice.Methods According to the"6S"evidence model,the evidence for non-pharmacological nutrition management in patients with cancer cachexia was systematically searched from domestic and international databases and websites,the retrieval time was from the establishment to September 2023.The quality of the included literature was critically appraised and the evidence were extracted,evaluated and integrated to form the best evidence.Results A total of 19 papers were selected,including 8 guidelines,2 clinical decisions,1 clinical pathway,2 position papers,3 systematic reviews,1 evidence summary and 2 expert consensus statements.and 22 pieces of evidence were finally extracted and summarized from 3 aspects:assessment and diagnosis of cancer cachexia,multidisciplinary team and management objectives,nutritional support.Conclusion The best evidence for non-pharmacological nutritional management in patients with cancer cachexia can provide a decision-making basis for carrying out nutritional interventions in patients with cancer cachexia,and it is recommended that clinical healthcare professionals translate the evidence to combine the specific clinical contexts and patients′wishes.

关 键 词：恶性肿瘤 恶病质 营养管理 营养评估 进食 证据总结 循证护理 

分 类 号：R473.73[医药卫生—护理学]