Staphylococcus aureus and biofilms:transmission, threats, and promising strategies in animal husbandry  

作　　者：Mengda Song Qi Tang Yakun Ding Peng Tan Yucheng Zhang Tao Wang Chenlong Zhou Shenrui Xu Mengwei Lyu Yueyu Bai Xi Ma 

机构地区：[1]State Key Laboratory of Animal Nutrition and Feeding,College of Animal Science and Technology,China Agricultural University,Beijing 100193,China [2]Key Laboratory of Innovative Utilization of Local Cattle and Sheep Germplasm Resources(Co‑Construction by Ministry and Province),Ministry of Agriculture and Rural Affairs,School of Agricultural Sciences,Zhengzhou University,Zhengzhou 450001,China

出　　处：《Journal of Animal Science and Biotechnology》2024年第4期1408-1423,共16页畜牧与生物技术杂志（英文版）

基　　金：supported by the National Natural Science Foundation of China (31930106 and U22A20514, U23A20232);the National Key R&D Program of China (2022YFD1300404);the 2115 Talent Development Program of China Agricultural University (1041-00109019);the Pinduoduo-China Agricultural University Research Fund (PC2023A01001);the Special Fund for Henan Agriculture Research System (HARS-2213-Z1)。

摘　　要：Staphylococcus aureus(S. aureus) is a common pathogenic bacterium in animal husbandry that can cause diseases such as mastitis, skin infections, arthritis, and other ailments. The formation of biofilms threatens and exacerbates S. aureus infection by allowing the bacteria to adhere to pathological areas and livestock product surfaces, thus triggering animal health crises and safety issues with livestock products. To solve this problem, in this review, we provide a brief overview of the harm caused by S. aureus and its biofilms on livestock and animal byproducts(meat and dairy products). We also describe the ways in which S. aureus spreads in animals and the threats it poses to the livestock industry. The processes and molecular mechanisms involved in biofilm formation are then explained. Finally, we discuss strategies for the removal and eradication of S. aureus and biofilms in animal husbandry, including the use of antimicrobial peptides, plant extracts, nanoparticles, phages, and antibodies. These strategies to reduce the spread of S. aureus in animal husbandry help maintain livestock health and improve productivity to ensure the ecologically sustainable development of animal husbandry and the safety of livestock products.

关 键 词：Animal husbandry BIOFILM MASTITIS Mitigation strategies Staphylococcus aureus 

分 类 号：S852.61[农业科学—基础兽医学]