某院非淋病尿道炎支原体感染情况及药敏结果分析  

Analysis of mycoplasma infection of non-gonorrheal urethritis and drug sensitivity results in a hospital

作　　者：江琼瑶 任宝军[1] 钱净[1] JIANG Qiong-yao;REN Bao-jun;QIAN Jing(Department of Laboratory,The First People's Hospital of Kunming,Yunnan Kunming 650011)

机构地区：[1]昆明市第一人民医院检验科,云南昆明650011

出　　处：《医学检验与临床》2024年第6期37-41,共5页Medical Laboratory Science and Clinics

摘　　要：目的:探讨昆明市第一人民医院近5年来泌尿道感染情况及药敏结果、流行状况,为临床治疗提供合理的用药依据。方法:回顾性收集昆明市第一人民医院2018年1月-2022年12月来自门诊及住院部的8453例作为研究对象,年龄14~95岁,采用珠海迪尔生物工程股份有限公司支原体试剂盒对送检样本进行检测。并与流行病学资料对比分析支原体感染流行状况。结果:近5年来8453例患者,检测支原体阳性为2834例,阳性率33.50%(2834/8453),其中以单一解脲脲原体为主,共2231例,占比26.40%(2231/8453),检出单一人型支原体119例,占比1.40%(119/8453),解脲+人型484例,占比5.72%(484/8453),药敏结果提示,多西环素、交沙霉素、米诺环素三者的耐药率最低。结论:昆明市第一人民医院检测支原体感染以解脲脲原体为主,且解脲脲原体(ureaplasma urealyticum,Uu)和人型支原体,(mycoplasmahominis,Mh)混合感染的患者对药物的敏感率下降、耐药率上升。目前推荐临床送检标本类型生殖道分泌物,治疗首选药物是交沙霉素、多西环素、米诺环素。Objective:To explore the urinary tract infections and drug sensitivity results and epidemic status in Kunming First People's Hospital in the past 5 years,and to provide a reasonable way for clinical treatment.Methods:8453 cases from the outpatient and inpatient departments of Kunming First People's Hospital from January 2018 to December 2022 were retrospectively collected as study subjects,aged 14-95 years,and the samples sent for testing were tested by using Zhuhai Diel Bioengineering Co.The prevalence of mycoplasma infection in the First People's Hospital of Kunming was obtained by comparison and analysis with epidemiological data.Results:In the past 5 years,8453 patients,of which 2834 cases were tested positive,33.5%positive(2834/8453),of which 2231 cases were dominated by a single mycoplasma solan,accounting for 26.40%(2231/8453),the number of single human type mycoplasma 119,accounting for 1.40%(119/8453),the number of mycoplasma solani+human type accounted for 484,compared to 5.72%(484/8453),the drug sensitivity results suggest that the highest sensitivity rate of doxycycline,cross-axamycin and minocycline,and the lowest resistance rate of the three.Conclusion:Mycoplasma urealyticum(Uu)and mycoplasma hominis(Mh)mixed infections in the First People's Hospital of Kunming were mainly detected,and the drug sensitivity rate decreased and the drug resistance rate increased.The current recommendations for clinical delivery ofspecimen type secretions,and the drugs of choice for treatmentare crossspectin,doxycycline and minocycline.

关 键 词：非淋病尿道炎 解脲脲原体 人型支原体 感染 药敏结果 

分 类 号：R691.3[医药卫生—泌尿科学] R446.5[医药卫生—外科学]