早发女性冠心病患者单支病变的临床特点分析  

Clinical features of single-vessel disease in female patients with premature coronary heart disease

作　　者：李剑[1] 郭磊磊 刘丽[1] 张静珂 胡利 蔡莉娜 LI Jian;GUO Lei-lei;LIU Li;ZHANG Jing-ke;HU Li;CAI Li-na(Jiangyou People’s Hospital,Jiangyou 621700,China)

机构地区：[1]江油市人民医院,四川江油621700

出　　处：《心血管病防治知识（学术版）》2024年第5期3-6,共4页Prevention and Treatment of Cardiovascular Disease

摘　　要：目的 探索早发女性冠心病患者单支病变的临床特征。方法 本研究为回顾性研究,选取2017年1月至2019年12月于我院诊断为冠心病的早发女性患者(年龄<65岁)。根据冠脉CT/冠脉造影结果分为单支病变组和多支病变组。通过比较两组的基线资料、主要血液学检测指标、超声心动图指标、合并症等,探索冠脉特点为单支病变的早发女性患者的临床特征。结果 共纳入368例患者,其中单支病变组144例(39.1%),多支病变组224例(60.9%)。与多支病变组比较,单支病变组的发病年龄更小(P<0.05),吸烟史低(P<0.05),高密度脂蛋白胆固醇更低(P<0.05),同时单支病变组的患者诊断稳定型心绞痛患者数更多,而不稳定型心绞痛、心肌梗死的数量更少(P<0.05),且单支病变组左室射血分数更高(P<0.05)。结论 单支病变的早发女性冠心病患者的发病年龄更早,吸烟者更少,射血分数更高,多数为稳定型心绞痛患者,提示单支病变患者预后更好。Objective To investigate the clinical features of single-vessel disease in female patients with premature coronary heart disease.Methods A retrospective analysis was performed for the female patients,aged <65 years,who were diagnosed with premature coronary heart disease in Jiangyou People's Hospital from January 2017 to December 2019,and according to the results of coronary CT/coronary angiography,they were divided into single-vessel disease group and multi-vessel disease group.The two groups were compared in terms of baseline data,main hematological indicators,echocardiographic indicators,and comorbidities to explore the clinical features of single-vessel coronary artery lesions in female patients with premature coronary heart disease.Results A total of 368 patients were enrolled,with 144 patients(39.1%) in the single-vessel disease group and 224 patients(60.9%) in the multi-vessel disease group.Compared with the multi-vessel disease group,the single-vessel disease group had a significantly younger age(P<0.05),a significantly lower proportion of patients with a smoking history(P<0.05),and a significantly lower level of high-density lipoprotein cholesterol(P<0.05).Compared with the multi-vessel disease group,the single-vessel disease group had a significantly higher proportion of patients diagnosed with stable angina and a significantly lower proportion of patients with unstable angina or myocardial infarction(P<0.05),as well as a significantly higher left ventricular ejection fraction(P<0.05).Conclusion Female patients with premature coronary heart disease tend to have a younger age of onset of single-vessel disease,with a lower proportion of smokers and a higher ejection fraction,and most patients have stable angina,suggesting that patients with single-vessel disease tend to have a better prognosis.

关 键 词：早发冠心病 女性 单支病变 

分 类 号：R541.4[医药卫生—心血管疾病]