无偿献血中初筛丙氨酸转氨酶升高的原因及防控措施分析  

Analysis of the causes and prevention and control measures of the elevation of alanine aminotransferase in preliminary screening of voluntary blood donation

作　　者：仝锐 张玉朝 何立明 TONG Rui;ZHANG Yuchao;HE Liming(Component Department;Blood Donation Service Department;Quality Control Office,Nanyang Central Blood Station,Nanyang 473000,China)

机构地区：[1]南阳市中心血站成分科,河南南阳473000 [2]南阳市中心血站献血服务科,河南南阳473000 [3]南阳市中心血站质管办,河南南阳473000

出　　处：《临床医学研究与实践》2024年第22期36-39,共4页Clinical Research and Practice

摘　　要：目的分析无偿献血中初筛丙氨酸转氨酶升高的原因及防控措施。方法回顾性分析南阳市中心血站2022年1月至12月所有采血者(共19127人)的血样检测资料,经初筛检测637例血样存在丙氨酸转氨酶升高的情况,以此作为观察组,而经初筛未检出丙氨酸转氨酶升高的18490例血样作为对照组。统计并比较两组的基线资料,分析无偿献血中丙氨酸转氨酶升高的防控措施。结果两组研究对象的性别、年龄、职业情况无显著差异(P>0.05);观察组的体重71~80 kg、中重度脂肪肝、有吸烟史、有饮酒史、献血前3 d内有服药史、长期熬夜占比均显著高于对照组,差异具有统计学意义(P<0.05)。结论在无偿献血初筛丙氨酸转氨酶升高的原因中,肥胖、肝脏脂肪衰减指数、不良饮食和生活习惯、使用药物等为影响因素,可结合上述影响因素开展防控措施,做好献血前准备工作,避免不必要的医疗资源浪费和献血者损伤。Objective To analyze the causes and prevention and control measures of the elevation of alanine aminotransferase in preliminary screening of voluntary blood donation.Methods The blood sample test data of all blood collectors(19127 people in total)in Nanyang Central Blood Station from January to December 2022 were retrospectively analyzed.The blood samples of 637 cases with elevated alanine aminotransferase were detected by preliminary screening as observation group,while the blood samples of 18490 cases without elevated alanine aminotransferase were detected by preliminary screening as control group.The basic data of the two groups were statistically compared,and the prevention and control measures for the elevation of alanine aminotransferase in voluntary blood donation were analyzed.Results There were no significant differences in gender,age and occupation between the two groups(P>0.05);the proportions of body weight 71-80 kg,moderate to severe fatty liver,smoking history,drinking history,medication history within 3 days before blood donation,and long-term staying up late in the observation group were significantly higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Among the reasons for the elevation of alanine aminotransferase in preliminary screening of voluntary blood donation,obesity,liver fat attenuation index,bad diet and living habits,drug use and so on are influecing factors.Prevention and control measures can be carried out in combination with the above influencing factors,and preparation work before blood donation can be done to avoid unnecessary waste of medical resources and injury of blood donors.

关 键 词：无偿献血 丙氨酸转氨酶 防控措施 

分 类 号：R457.1[医药卫生—治疗学]