血液灌流联合持续静脉-静脉血液滤过治疗老年重度胡蜂蛰伤并多器官障碍综合征的临床效果  

Clinical effect of hemoperfusion and continuous veno-venous hemofiltration in the treatment of severe wasp stings complicated by multiple organ disfunction syndrome

作　　者：李文 雷淑霞 王山 张斌 何青鋆 张啸林 LI Wen;LEI Shuxia;WANG Shan;ZHANG Bin;HE Qingjun;ZHANG Xiaolin(Critical Care Medicine Department,People's Hospital of Shanyang County,Shangluo 726400,China)

机构地区：[1]山阳县人民医院重症医学科,陕西商洛726400

出　　处：《临床医学研究与实践》2024年第22期92-95,共4页Clinical Research and Practice

摘　　要：目的探讨血液灌流联合持续静脉-静脉血液滤过治疗老年重度胡蜂蛰伤并多器官障碍综合征(MODS)的临床效果。方法选取本院收治的老年重度蜂蛰伤并MODS患者14例,给予常规治疗的同时,患者均接受血液灌流联合持续静脉-静脉血液滤过治疗。分析患者的治疗效果。结果治疗后,患者的血小板计数和平均动脉压高于治疗前,谷丙转氨酶、谷草转氨酶、总胆红素、肌酐、肌酸激酶同工酶、肌红蛋白、白细胞介素-6、C反应蛋白水平及急性生理与慢性健康评分(APACHEⅡ)、序贯器官衰竭评估(SOFA)评分低于治疗前,凝血酶原时间短于治疗前(P<0.05)。14例患者的住院时间为9~39 d,平均(19.4±7.8)d,经积极治疗后均好转出院。结论血液灌流联合连续静脉-静脉血液滤过治疗老年重度胡蜂蛰伤并MODS患者的临床效果显著。Objective To investigate the clinical effect of hemoperfusion and continuous veno-venous hemofiltration in the treatment of severe wasp stings complicated by multiple organ disfunction syndrome(MODS).Methods A total of 14 elderly patients with severe wasp stings and MODS admitted in our hospital were selected.All patients received hemoperfusion combined with continuous veno-venous hemofiltration treatment in addition to conventional treatment after admission.The therapeutic effect of patients were analyzed.Results After treatment,the platelet count and mean arterial pressure of the patients were higher than those before treatment,the alanine aminotransferase,aspartate aminotransferase,total bilirubin,creatinine,creatine kinase isoenzyme,myoglobin,interleukin-6,C-reactive protein levels and Acute Physiology and Chronic Health Evaluation(APACHEⅡ)and Sequential Organ Failure Assessment(SOFA)scores were lower than those before treatment,and the prothrombin time was shorter than that before treatment(P<0.05).The hospitalization time of 14 patients was 9-39 d,with an average of(19.4±7.8)d,all patients were improved and discharged after active treatment.Conclusion Hemoperfusion combined with continuous veno-venous hemofiltration has a significantly clinical effect on elderly patients with severe wasp stings and MODS.

关 键 词：血液灌流 持续静脉-静脉血液滤过 重度胡蜂蛰伤 多器官障碍综合征 

分 类 号：R646[医药卫生—外科学]