基于隐结构模型联合频繁项集的针灸治疗弱精子症不育患者的辨证取穴规律  

Acupoint Selection Rules of Acupuncture and Moxibustion Treatment of Asthenozoospermia Based on Latent Structure Model and Frequent Item Set

作　　者：何瑞宣 孙自学[2] 华众 张芳[1] 张迪[1] 胡创政 HE Ruixuan;SUN Zixue;HUA Zhong;ZHANG Fang;ZHANG Di;HU Chuangzheng(The Second Clinical College of Medicine,Henan University of Chinese Medicine,Zhengzhou 450000,China;Reproductive and Andrology Diagnosis and Treatment Center of Henan Province Hospital of Traditional Chinese Medicine,Zhengzhou 450000,China)

机构地区：[1]河南中医药大学第二临床医学院,郑州450000 [2]河南省中医院生殖医学诊疗中心,郑州450000

出　　处：《世界中医药》2024年第14期2185-2190,共6页World Chinese Medicine

基　　金：国家自然科学基金项目(82274536);河南省中医药科学研究重大专项课题(2022ZYZD09);河南省防治生殖障碍疾病中医药重点实验室(2021ZDSYS10)。

摘　　要：目的:探讨针灸治疗弱精子症不育患者的辨证取穴规律,为临床治疗弱精子症不育患者提供帮助。方法:检索国家知识基础设施数据库(CNKI)、中国生物医学文献数据库(CBM)、中国学术期刊数据库(CSPD)及中文科技期刊数据库(CCD)等数据库有关针灸治疗弱精子症的相关文献,提取症状、取穴处方信息构建医案数据库,采用隐结构模型、频繁项集的数据挖掘方法,分析针灸治疗弱精子症的辨证取穴规律。结果:纳入文献35篇,涉及症状62种,穴位49个。高频症状包括腰酸、神疲乏力等,高频腧穴包括关元、肾俞等。对症状、腧穴、证型进行频繁项集分析,挖掘出症状-腧穴频繁项集4项,包括耳鸣+头晕+腰酸+关元+肾俞等;证型-症状频繁项集4项,包括肾精亏虚证+健忘+性欲淡漠+神疲乏力+脉细等;证型-症状-腧穴频繁项集4项,包括肾精亏虚证+性欲淡漠+神疲乏力+头发易脱+关元等。结论:针灸治疗弱精子症多以关元、肾俞、足三里为主穴。Objective:To explore the acupoint selection rules of acupuncture and moxibustion treatment of asthenozoospermia-induced infertility based on syndrome differentiation and provide assistance for clinical treatment of asthenozoospermia.Methods:Relevant literature on acupuncture and moxibustion treatment for asthenozoospermia was searched from databases including the China National Knowledge Infrastructure(CNKI),Chinese Biomedical Literature Database(CBM),China Science Periodical Database(CSPD),and Chinese Sci-tech Journal Database(CCD).Symptoms and acupuncture prescriptions were extracted to construct a case database.Data mining methods,such as the latent structure model and frequent item set,were used to analyze the acupoint selection rules of acupuncture and moxibustion treatment of asthenozoospermia based on syndrome differentiation.Results:Thirty-five articles were included,involving 62 symptoms and 49 acupoints.High-frequency symptoms included lower back soreness and fatigue,while high-frequency acupoints included Guanyuan(CV4) and Shenshu(BL23).Frequent item set analysis of symptoms,acupoints,and syndromes revealed four symptom-acupoint frequent item sets,such as tinnitus+dizziness+lower back soreness+Guanyuan(CV4)+Shenshu(BL23);four syndrome-symptom frequent item sets,such as kidney essence deficiency+forgetfulness+low libido+fatigue+thready pulse;four syndrome-symptom-acupoint frequent item sets,such as kidney essence deficiency+low libido+fatigue+hair loss+Guanyuan(CV4).Conclusion:The primary acupoints used in the treatment of asthenozoospermia are Guanyuan(CV4),Shenshu(BL23),and Zusanli(ST36).

关 键 词：隐结构模型 频繁项集 弱精子症 辨证取穴规律 数据挖掘 Apriori算法 穴位 针灸 

分 类 号：R245[医药卫生—针灸推拿学]