高频重复经颅磁刺激在酒精成瘾及酒精性精神行为障碍患者中的临床疗效  

Clinical Efficacy of High-frequency Repetitive Transcranial Magnetic Stimulation in Patients with Alcohol Addiction and Alcoholic Psychobehavioral Disorders

作　　者：沈青峰 孙玉 史汉青 李海玲 朱相华 SHEN Qingfeng;SUN Yu;SHI Hanqing;LI Hailing;ZHU Xianghua(Xuzhou East Hospital Affiliated to Xuzhou Medical University,Xuzhou,Jiangsu Province,221004 China)

机构地区：[1]徐州医科大学附属徐州东方医院,江苏徐州221004

出　　处：《系统医学》2024年第11期48-50,54,共4页Systems Medicine

摘　　要：目的 探究高频重复经颅磁刺激在酒精成瘾及酒精性精神行为障碍患者中的临床疗效。方法 选取2021年7月—2023年7月徐州医科大学附属徐州东方医院收治的80例酒精成瘾及酒精性精神行为障碍患者作为研究对象。采取红蓝球法随机分为对照组、观察组,各40例。对照组予以奥沙西泮和复合维生素B治疗,观察组在对照组基础上实施高频重复经颅磁刺激治疗。比较两组临床疗效、认知功能及成瘾情况。结果 观察组治疗总有效率(95.00%)高于对照组(80.00%),差异有统计学意义(χ^(2)=4.114,P<0.05)。观察组洛文斯顿作业疗法认知评定量表评分高于对照组,强制饮酒量表、冲动行为量表评分均低于对照组,差异有统计学意义(P均<0.05)。结论 采用高频重复经颅磁刺激有助于降低患者的成瘾性,并改善其冲动性和认知功能。Objective To explore the clinical efficacy of high-frequency repetitive transcranial magnetic stimulation in patients with alcohol addiction and alcoholic psychobehavioral disorders.Methods A total of 80 patients with alco-hol addiction and alcoholic psychobehavioral disorder admitted to Xuzhou East Hospital Affiliated to Xuzhou Medical University from July 2021 to July 2023 were selected as the study objects.The patients were randomly divided into control group and observation group by red and blue ball method,40 cases in each group.The control group was treated with oxazepam and compound vitamin B,and the observation group was treated with high-frequency repetitive transcranial magnetic stimulation based on the control group.The clinical efficacy,cognitive function and addiction status of the two groups were compared.Results The total effective rate of observation group(95.00%)was higher than that of control group(80.00%),and the difference was statistically significant(χ^(2)=4.114,P<0.05).The Lovingston oc-cupational therapy cognitive rating scale score of the observation group was higher than that of the control group,and the scores of the compulsive drinking scale and impulsive behavior scale were lower than those of the control group,and the differences were statistically significant(all P<0.05).Conclusion The use of high-frequency repetitive transcranial magnetic stimulation helps to reduce addiction in patients and improve their impulsivity and cognitive function.

关 键 词：高频重复经颅磁刺激 酒精成瘾 酒精性精神行为障碍 临床效果 认知功能 酒精依赖度 

分 类 号：R4[医药卫生—临床医学]