探究WBC、CRP、PCT与SAA联合检测在儿童上呼吸道感染诊断中的临床应用价值  

Exploring the Clinical Application Value of Combined Detection of WBC,CRP,PCT and SAA in the Diagnosis of Upper Respiratory Tract Infections in Children

作　　者：靳娜娜 张召涛 战义梅 JIN Nana;ZHANG Zhaotao;ZHAN Yimei(Department of Laboratory,Laixi Hospital of Traditional Chinese Medicine,Laixi,Shandong Province,266600 China;Pingdu Dermatologic Disease Control Station,Pingdu,Shandong Province,266700 China)

机构地区：[1]莱西市中医医院检验科,山东莱西266600 [2]平度市皮肤病防治站,山东平度266700

出　　处：《系统医学》2024年第11期127-130,共4页Systems Medicine

摘　　要：目的探究白细胞计数(White Blood Cell Count,WBC)、C反应蛋白(C-Reactive Protein,CRP)、降钙素原(Procalcitonin,PCT)、血清淀粉样蛋白A(Serum Amyloid A,SAA)检测在儿童上呼吸道感染诊断中的临床应用价值。方法回顾性选取2023年7月—2024年2月于莱西市中医医院检验科就诊的80例儿童上呼吸道感染患儿临床资料,纳入疾病组,同期选取在本院接受健康体检的80名健康儿童临床资料,纳入健康组,两组研究对象均进行了WBC、CRP、PCT与SAA检测,对比两组检测水平,以及上述指标单独及联合检测的诊断效能。结果疾病组WBC(16.32±2.39)×10^(9)/L、CRP(36.52±7.25)mg/L、PCT(3.45±0.80)ng/mL与SAA(116.52±18.58)mg/L水平均高于健康组,差异有统计学意义(t=28.915、35.701、37.563、52.364,P均<0.05)。联合检测的诊断效能均优于单一检测(P均<0.05)。结论WBC、CRP、PCT与SAA联合检测在儿童上呼吸道感染诊断中具有较高的临床应用价值,能显著提高诊断的敏感度和特异度,降低误诊和漏诊率,为临床诊断和治疗提供有力支持。Objective To investigate the clinical application value of white blood cell count(WBC),C-reactive pro-tein(CRP),procalcitonin(PCT),and serum amyloid A(SAA)tests in the diagnosis of upper respiratory tract infections in children.Methods The data of 80 children with upper respiratory tract infections in children attending the Department of Laboratory of Laixi Hospital of Traditional Chinese Medicine from July 2023 to February 2024 were retrospectively collected and included in the disease group.During the same period,the data of 80 healthy children who received health checkups in our hospital were collected and included in the health group.WBC,CRP,PCT and SAA tests were performed in both groups to compare the levels of these tests and the diagnostic efficacy of the above indicators alone and in combination.Results The levels of WBC(16.32±2.39)×10^(9)/L,CRP(36.52±7.25)mg/L,PCT(3.45±0.80)ng/mL and SAA(116.52±18.58)mg/L in the disease group were higher than those in the health group,and the differences were statistically significant(t=28.915,35.701,37.563,52.364,all P<0.05).The diagnostic efficacy of the combined tests were all better than that of the single tests(all P<0.05).Conclusion The combination of WBC,CRP,PCT and SAA has high clinical application value in the diagnosis of children's upper respiratory tract infections,which can significantly improve the sensitivity and specificity of diagnosis,reduce the rate of misdiagnosis and omission,and provide strong support for clinical diagnosis and treatment.

关 键 词：儿童 上呼吸道感染 白细胞计数 C反应蛋白 降钙素原 血清淀粉样蛋白A 诊断效能 

分 类 号：R725[医药卫生—儿科]