印片细胞在乳腺肿瘤术中快速病理诊断中的准确度评价  

Evaluation of Accuracy of Imprinted Cells in Rapid Pathologic Diagnosis of Breast Tumors During Surgery

作　　者：成慧[1] 张海霞[1] 董惠[1] CHENG Hui;ZHANG Haixia;DONG Hui(Shouguang People's Hospital,Shouguang,Shandong Province,262700 China)

机构地区：[1]寿光市人民医院,山东寿光262700

出　　处：《系统医学》2024年第11期135-138,共4页Systems Medicine

摘　　要：目的 探讨乳腺肿瘤术中快速病理诊断中印片细胞的诊断效果及准确度。方法 选取2022年8月—2023年10月寿光市人民医院收治的100例疑似乳腺肿瘤患者为研究对象,所有患者术中送检新鲜肿瘤组织标本,进行病理检查,包括冰冻切片、印片细胞,以术后病理诊断结果为金标准,分析上述不同术中快速病理诊断的价值。结果 术后病理诊断显示,100例疑似患者中,阳性48例,冰冻切片、印片细胞诊断显示阳性分别为50例、48例,检出率对比,差异无统计学意义(P>0.05);印片细胞诊断特异度(96.15%)、准确度(96.00%)、敏感度(95.83%)均高于冰冻切片(76.92%、78.00%、79.17%),差异有统计学意义(χ^(2)=8.254、14.323、6.095,P均<0.05)。结论 印片细胞具有较高的特异度、准确度、敏感度,可以更好地指导针对性治疗。Objective To investigate the diagnostic effect and accuracy of imprinted cells in rapid pathologic diagno-sis of breast tumor during surgery.Methods From August 2022 to October 2023,a total of one hundred patients with suspected breast tumors treated in Shouguang People's Hospital were selected as the study objects.Fresh tumor tissue samples of all patients were sent for intraoperative examination,and pathological examinations were performed,including frozen sections and printed cells.Based on the postoperative pathological diagnosis results as the gold standard,the value of the above rapid pathological diagnosis in different operations was analyzed.Results Postoperative pathological diagnosis showed that among the 100 suspected patients,48 cases were positive,while frozen section and imprinted cell diagnosis showed positive cases in 50 cases and 48 cases,respectively.There was no statistically significant difference in the detection rate of the two groups(P>0.05).The specificity(96.15%),accuracy(96.00%)and sen-sitivity(95.83%)of imprinted cells were higher than those of frozen sections(76.92%,78.00%,79.17%),the differences were statistically significant(χ^(2)=8.254,14.323,6.095,all P<0.05).Conclusion Imprinted cells has high speci-ficity,accuracy and sensitivity,which can better guide the targeted treatment.

关 键 词：乳腺肿瘤 术中快速病理诊断 印片细胞 诊断价值 

分 类 号：R59[医药卫生—内科学]