临床药师参与一例二尖瓣后叶脱垂并关闭不全行MitraClip术合并房颤患者抗栓治疗的药学监护  

Clinical Pharmacists Participated in the Pharmaceutical Care of a Case of Mitral Valve Prolapse with Incomplete Closure and Antithrombotic Therapy for Atrial Fibrillation Patients undergoing MitraClip Surgery

作　　者：武珊珊 闫佳佳[2] 王茜 WU Shanshan;YAN Jiajia;WANG Qian(Department of Pharmacy,Panyu District Maternal and Child Health Care Hospital,Guangzhou,Guangdong Province,511400 China;Department of Pharmacy,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou,Guangdong Province,510080 China)

机构地区：[1]广州市番禺区妇幼保健院药剂科,广东广州511400 [2]中山大学附属第一医院药学部,广东广州510080

出　　处：《系统医学》2024年第11期180-184,共5页Systems Medicine

摘　　要：目的 探讨二尖瓣后叶脱垂并关闭不全行MitraClip术合并房颤患者抗栓治疗的个体化给药策略。方法 回顾性选取2023年2—3月中山大学附属第一医院收治的1例二尖瓣后叶脱垂并关闭不全行MitraClip术合并房颤患者的抗栓方案,叙述其治疗过程,根据患者临床症状、体征及实验室检查,优化抗栓治疗方案,为临床提供合理用药建议。归纳了二尖瓣后叶脱垂并关闭不全行MitraClip术合并房颤患者的抗栓策略,结合国内外指南文献,总结药物的使用情况,优化临床治疗方案。结果 根据患者肝肾功能变化情况,调整抗栓药物给药剂量,保障患者用药安全。结论 临床药师参与患者治疗,为临床提供合理用药建议,保证临床用药安全。Objective To investigate the individualized administration strategy of antithrombotic therapy in patients with atrial fibrillation who underwent MitraClip surgery for posterior mitral valve prolapse with incomplete closure.Methods The antithrombotic regimen of a patient with posterior mitral valve prolapse with incomplete closure and Mi-traClip combined with atrial fibrillation in the First Affiliated Hospital of Sun Yat-sen University from February to March 2023 was retrospectively selected,and the treatment process was described.According to the clinical symp-toms,signs and laboratory examination of the patient,the antithrombotic regimen was optimized,and rational drug use suggestions were provided for the clinic.The antithrombotic strategies for patients with atrial fibrillation who under-went MitraClip surgery with posterior mitral valve prolapse and incomplete closure were summarized.Combined with domestic and foreign guidelines,the use of drugs was summarized and clinical treatment was optimized.Results Ac-cording to the changes of liver and kidney function of patients,the dose of antithrombotic drugs should be adjusted to ensure the safety of patients.Conclusion Clinical pharmacists'participating in the treatment of patients provides sug-gestions for rational drug use,and ensures the safety of clinical drug use.

关 键 词：MitraClip术 抗栓治疗 用药安全性 

分 类 号：R973[医药卫生—药品]